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Furthermore, SARS-CoV-2 struggles to survive in high-temperature settings besides other factors crucial for virus transmission, such as overcrowding and ill ventilation with winter seasons (76). In addition, the decrease in lung functions and the increase in aggravations for COPD patients were associated with cold temperatures (77). Besides, DTR considers a fixed temperature parameter, which is a key to variability of temperature to estimate influences on human health, including morbidity and mortality (78). Furthermore, abrupt variations of temperature add to the burdens of the respiratory and cardiac systems causing high levels of DTR and cardiopulmonary symptoms (72). Scientists reported that cold and low humidity conditions elevate the possibility of respiratory infection (79), where humidity was the principal key to mortality. Decreasing the humidity degree may cause higher mortality rates, most likely by influenza-related mechanisms (80, 81). Some reports also indicated that COVID-19 mortality decreased only with higher absolute humidity (82). In addition, the expansion of the influenza pandemic virus is very effective under dry and cold atmosphere (83), and the lesser the absolute humidity, the higher the survival rate of the influenza virus (84) that could be similar to the coronavirus. Thus, the elevation of COVID-19 mortality could also be associated to low humidity levels in winter. Nevertheless, it is worth noting that the previous expectations were during the first 3 months of the commencement of the pandemic, but now and after 6 months, it is not clear that the virus is less infectious during the summer. For example, the countries of southern Europe and the countries of the Middle East, which are now entering summer, are not assisting to decreases in infection rate, and this is probably due to less restriction to circulation and confinement. But at the same time, it appears that, in these circumstances, if no measures are considered, the virus has the potential to spread and infect a high number of people. Control of the Spreading of the Virus Raj et al. (27) confirmed that coughing, sneezing, and materials contaminated with SARS-CoV-2 could be highly contagious with the disease. Feces also were found to be contaminated with the virus, which develops an unprecedented chance of feces–mouth transmission. An early report on 138 patients described that 41% of the patients probably were infected by nosocomial infections. Of these patients, 40 of them were healthcare employees and 17 were having previous illnesses (5). Thus, extreme vigilance is imperative for saving populations that communicate with patients or infected people. Using disinfectants such as soap and alcohol-based antiseptics is effective in controlling viral spreading. Soap is a surfactant compound that has a hydrophilic head and a hydrophobic tail. Thus, when the lipid viral membrane encounter the amphipathic soap molecules, the hydrophilic head is attracted to water while the hydrophobic tail sticks to the lipid membrane, so the viruses are lifted off and washed away. As viruses become displaced, more soap molecules surround and destroy them by breaking open the lipid membrane of the virus. Alcoholic-based disinfectants also disrupt the lipid viral membrane, but in a different way from soaps, where most of these disinfectants contain either ethanol or isopropanol or a mixture between them dissolved in water. These alcohols are small polar molecules that can interact with the surface of the lipid layer and subsequently disrupt the viral membrane structure and breaking open the virus when alcohols are present in sufficient concentrations. Furthermore, denaturation of viral proteins is another mechanism of alcohol-based antiseptics to disrupt proteins structure on the surface of SARS-CoV-2 viruses and inactivate them. Alcohol inactivates the virus by displacing the hydrogen bonds between amino acids that maintain the shape of viral proteins, causing the loss of function and structure of these proteins. It is worth noting that it is difficult to disrupt viral proteins by this method in the absence of water; therefore, 60–80% alcohol products are most effective than those of 100%. Individual Roles Using face masks represent one of the early steps of protection to reduce the infection hazard. Both surgical masks and N95 respirator masks (series # 1860s) could prevent infection (85). The runny droplets from the infected cases can pass through the atmosphere or hold onto materials' surfaces. This can be prevented by wearing surgical face masks (86). However, inhalation of virions (10–80 nm) can be protected only by N95 (series # 1860s) masks, with 5% of the virions capable of sneaking; SARS-CoV-2 is identical to SARS-CoV in size with an average of 85 nm (86). Thus, healthcare employees who communicate with infected cases should wear N95 (series # 1860s) masks and avoid surgical masks (87). Moreover, healthcare employees must have adequate medical clothes for protection against viruses. On January 22, 2020, a physician contracted SARS-CoV-2 despite wearing an N95 mask; SARS-CoV-2 could enter the body via inflamed eyes. Thus, viruses can also be transmitted through the eyes (19). It is strongly recommended that healthcare employees wear clear face shields or goggles during handling infected patients. For the infected regions, it is strongly recommended all people wash their hands with suitable disinfectant several times (personal cleanliness), stay indoors, and reduce direct contact with infected patients. Three feet is considered a recommended distance that is prompt for communicating with a patient (88). Governmental Roles SARS-CoV-2 is considered a novel viral infection to the world and happens to be identical to SARS-CoV as announced last January 2020 (89). It caused a massive uproar in China as it was a throwback to the SARS outbreak in 2003. However, the government reassured people through spreading awareness about how to decrease contagiousness and lower infectivity from human to human to avoid an outbreak, easing the distress of the citizens during the spring festival. Later on, the disease