Hydrazine Effects in Humans starts on page 139 (references to alopecia on page 145)

Sotaniemi et al. (1971) describes the death of a 59-year-old male machinist who handled hydrazine hydrate once each week over a period of 6 months. No account of his work practice or percutaneous hydrazine uptake was provided. He complained of conjunctivitis, tremors, and lethargy after each exposure. On the last day of his employment, he developed gastrointestinal distress and fever. On admission to the hospital, the patient presented with atrial fibrillation; stomatitis; conjunctivitis; upper abdominal pain and enlarged abdomen; jaundice and a tender, palpable liver; elevated bilirubin and creatinine; oligouria with protein and erythrocytes in his urine; and black feces. Chest X-rays revealed pleural effusions and shadowing. He died 15 days after hospitalization. Autopsy revealed tracheitis, bronchitis, and pneumonia; renal tubular necrosis, hemorrhage, and inflammation; and focal hepatocellular necrosis. An enlarged and discolored heart exhibiting degeneration of the cardiac muscle also was noted, but the relationship of that observation to hydrazine exposure was unclear. No empirical hydrazine concentrations were obtained, but subsequent simulations suggested a workplace air concentration of about 0.05 ppm.

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