Jsmc-10299

THE RISK OF LOW VITAMIN D IN THE DEVELOPMENT OF PREECLAMPSIA

Shanga Abdulla Sleman a, Ghada Saadallah Alsakkal b, and Shayan Jalal Khalaf c

a Obstetrics and Gynecology Trainee, Sulaimani Maternity Teaching Hospital, Sulaimani, Kurdistan Region, Iraq.

b Hawler Medical University, Kurdistan Region, Iraq.

c Department of Gynecology and Obstetrics, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

Submitted: 16/9/2020; Accepted: 6/2/2021; Published: 21/6/2021

DOI Link: https://doi.org/10.17656/jsmc.10299

ABSTRACT

Background

Preeclampsia is new-onset hypertension and proteinuria after 20 gestational weeks. A low vitamin D level is thought to associate with a higher risk of preeclampsia.

Objectives

We aimed to find the association of serum vitamin D levels with preeclampsia in our population, in which vitamin D deficiency is common.

Patients and Methods

A prospective cohort study was performed on 80 pregnant women who were admitted to Sulaimani Maternity Teaching Hospital, Sulaimani, Kurdistan, Iraq. The women were collected from October 1, 2019, to March 13, 2020. The women were randomly selected and enrolled into three groups according to their clinical features of preeclampsia; no features of preeclampsia, a mild degree of preeclampsia, and severe form of preeclampsia. The inclusion criterion was pregnant women, and exclusion criteria were women with a history of hypertension, history of proteinuria before pregnancy, and refusal to participate. Demographic features and detailed clinical examination were recorded. Also, the serum vitamin D (ng/dL) was measured by Cobas ® 6000 analyzer machine (F. Hoffmann-La Roche Ltd).

Results

The mean ± SD (standard deviation) of participants’ age was 31.33 ± 6.05 years, and there were no significant differences in demographic features among the three groups. Systolic and diastolic blood pressures among the three groups were significantly different. There was no significant association between pregnant women and serum vitamin D levels. However, all of the preeclamptic women had either deficient or insufficient serum vitamin D levels.

Conclusion

There was no significant association between serum vitamin D levels in pregnant women and the occurrence of preeclampsia.

KEYWORDS

Preeclampsia; Vitamin D; Pregnancy; Sulaimani.

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