Ulcerative Colitis (UC)

Truelove & Witts Severity index

• • Severity score for ulcerative colitis

Mayo Score/Disease Activity Index 

• Severity score for ulcerative colitis

• Requires clinical judgement and endoscopic analysis

1. A patient presents with continuous inflammation of the inner mucosal lining that starts at the rectum and extends to the sigmoid colon. They report having 5 additional stools per day with blood, but no fever or anemia. Which of the following is the best classification of their colitis? 

a) Mild Proctitis

b) Mild procotosigmoiditis

c) Moderate proctosigmoiditis

d) Moderate left-sided colitis

2. All of the following signs/symptoms may be indicative of ulcerative colitis except

a) Blood or mucous in the stool

b) Fever

c) Vomiting

d) Abdominal distension

3. Which of the following would be MOST appropriate for inducing remission in mild distal ulcerative colitis? 

a) Topical aminosalicylate

b) Oral corticosteroid

c) TNF-alpha inhibitor

d) Tofacitinib

4. Which of the following statements is TRUE regarding aminosalicylates?

a) 5-ASA contains acetylsalicylic acid 

b) 5-ASA enema's are most useful for proctitis

c) Average onset is ~6 weeks 

d) Combination oral + topical improves efficacy 

5. All of the following are side effects of corticosteroids except

a) Hypoglycemia 

b) Cushingoid features

c) Skin thinning

d) GI bleed