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Mineral bone disease in CKD results from disruptions in calcium, phosphate, parathyroid hormone, and vitamin D regulation due to kidney dysfunction. This leads to bone demineralization, increased fracture risk, and vascular calcification, contributing to cardiovascular complications.
Tools + Resources
Tools + Resources
BC renal website http://www.bcrenal.ca/
BC Renal Muscle Cramp Management
BC Renal Pruritus Management
Student Guide
Student Guide
MBD in CKD.docx.pdfTest Your Knowledge
Test Your Knowledge
What is a primary cause of mineral and bone disorders (MBD) in CKD?
a) Overproduction of calcitriol
b) Impaired kidney function leading to disrupted balance of minerals and hormones
c) Excess calcium excretion by the kidneys
d) Decreased PTH production
Which of the following processes stops in CKD, contributing to MBD?
a) Activation of vitamin D into calcitriol
b) Removal of excess potassium from the blood
c) Excretion of sodium
d) Production of insulin
Hyperphosphatemia in CKD patients is associated with which major complication?
a) Hypoglycemia
b) Osteoporosis
c) Vascular calcification
d) Hypokalemia
What is the threshold value to treat hyperphosphatemia based on phosphate levels?
a) >0.8 mmol/L
b) >1.5 mmol/L for multiple readings
c) <0.8 mmol/L
d) >2.2 mmol/L
Which medication is reserved for patients with hyperparathyroidism and high calcium levels?
a) Cholecalciferol
b) Alfacalcidol
c) Calcitriol
d) Cinacalcet
Answer Key
Answer Key
b
a
c
b
d
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