Cardiovascular Disease & Chronic Kidney Disease

Tools + Resources

Estimates 10-year risk of heart attack in patients 30-79 years old with no history of CHD or diabetes [does NOT include CKD as a variable]

Calculates a person's risk of heart attack or stroke over the next 10 years [accounts for renal dysfunction]

Recommendations for dose adjustments in patients during intermittent hemodialysis

CVD and CKD.pdf

Which of the following screening tools would be most appropriate to calculate a patient's 10-year risk of experiencing a cardiovascular event if they have chronic kidney disease?

a) Framingham

b) Sparc Tool

c) QRISK 3

d) They are all equally appropriate

a) Heart failure

b) Chronic kidney disease

c) Diabetes

d) Dyslipidemia

a) CKD is considered a high-risk "statin-indicated" condition

b) CKD increases the risk for statin-associated myopathies

c) Atorvastatin requires dose adjustment in patients with eGFR < 30 ml/min

d) Statins should not be initiated in patients with eGFR < 15 ml/min

A 50 year old patient presents with hypertension and CKD. Their blood pressure is 145/70 mmHg and their eGFR is 45 ml/min. They are currently taking ramipril 5 mg po BID. Which of the following interventions would be MOST appropriate for this patient?

a) Add amlodipine 2.5 mg po daily

b) Add hydrochlorothiazide 12.5 mg po daily

c) Reduce ramipril to 5 mg po daily

d) a and c

Which of the following statements is TRUE regarding HFrEF treatment in patients with CKD?

a) Carvedilol requires dose adjustments in patients with eGFR < 20 ml/min

b) An increase in SCr by up to 15% is considered acceptable after starting an ACEI or ARB

c) Spironolactone may cause worsening renal function and should be discontinued in patients with eGFR < 30 ml/min

d) Empagliflozin should be discontinued in patients with eGFR < 25 ml/min

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