Crohn's Disease (CD)

Crohn's Disease Activity Index 

• For assessing the severity of Crohn's disease

• Requires subjective patient input

• Correlates poorly with score of endoscopic disease severity, fecal calprotectin and serum biomarkers of inflammation (i.e. CRP)

1. Which of the following statements regarding Crohn's disease is correct? 

a) Inflammation extends anywhere in the GI tract

b) Inflammation that is continuous

c) Inflammation of the submucosal layer of the GI tract only 

d) All of the above 

2. Which of the following is an extraintestinal symptom of Crohn's disease? 

a) Abdominal pain

b) Decreased appetite

c) Fever

d) Episcleritis

3. What are the goals of therapy for crohn's disease? 

a) Maintain remission and prevent relapse

b) Prevent complications

c) Cure disease

d) a and b 

4. All of the following are predictors of severe disease except

a) Smoking

b) low CRP and fecal calprotectin

c) Early use of corticosteroids

d) Deep ulceration on endoscopy 

5. All of the following may be used for maintenance of crohn's disease except

a) Methotrexate

b) Azathioprine or 6MP

c) Prednisone

d) TNF-alpha inhibitor