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Chronic kidney disease (CKD) patients frequently experience symptoms and complications that affect their quality of life, with some of the most bothersome including persistent itching (uremic pruritus) and muscle cramps. Symptom management aims to relieve these discomforts through targeted therapies, lifestyle adjustments, and ongoing assessment.
Tools + Resources
Tools + Resources
BC renal website http://www.bcrenal.ca/
http://www.bcrenal.ca/resource-gallery/Documents/Management%20of%20Pruritus%20in%20Patients%20with%20Chronic%20Kidney%20Disease.pdf
Student Guide
Student Guide
CKD sx management.pdfTest Your Knowledge
Test Your Knowledge
What is the most common location for pruritus in CKD patients?
a) Back
b) Hands and arms
c) Lower extremities
d) Abdomen
The Modified Edmonton Symptoms Assessment Score (ESAS) is used for patients with:
a) eGFR >60 ml/min/1.73m²
b) eGFR <15 ml/min/1.73m² or significant CKD-related symptoms
c) All dialysis patients regardless of eGFR
d) eGFR between 30–59 ml/min/1.73m²
What is a non-pharmacological recommendation for managing muscle cramps in CKD?
a) Use of antihistamines
b) Avoiding all physical activity
c) Drink more water
d) Applying hot or cold compresses
Which is a first-line pharmacological treatment for pruritus in CKD patients?
a) Gabapentin
b) Sertraline
c) 1st generation antihistamines (e.g., Hydroxyzine, Diphenhydramine)
d) Capsaicin 0.025% cream
Gabapentin for muscle cramps or pruritus in CKD patients requires:
a) No dose adjustment
b) Renal dosing adjustment
c) Pre-treatment with antihistamines
d) Use only if pregabalin fails
Answer Key
Answer Key
a
b
d
c
b
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