v.4 n.6 August

Parana Journal of Science and Education. v.4, n.6, August (2018).

Summary

ANovel Approach to Reduce Toxicities and to Improve Bioavailabilities of DNA/RNAof Human Cancer Cells–Containing Cocaine (Coke), Lysergide (Lysergic AcidDiethyl Amide or LSD), Δ9–Tetrahydrocannabinol (THC) [(–)–trans–Δ⁹–Tetrahydrocannabinol],Theobromine (Xantheose),Caffeine, Aspartame (APM) (NutraSweet) and Zidovudine (ZDV)[Azidothymidine (AZT)] as Anti–Cancer Nano Drugs by Coassembly of DualAnti–Cancer Nano Drugs to Inhibit DNA/RNA of Human Cancer Cells Drug Resistance.

Alireza Heidari and Ricardo Gobato. Parana J. Sci. Educ., v.4, n.6, (1-17), August 9, 2018.

DOI: doi.org/10.5281/zenodo.3843554

Abstract

The aim of the present study was to reduce toxicities and to improve bioavailabilities of DNA/RNA of human cancer cells–containing Cocaine (Coke), Lysergide (Lysergic Acid Diethyl Amide or LSD), Δ⁹–Tetrahydrocannabinol (THC) [(–)–trans–Δ⁹–Tetrahydrocannabinol], Theobromine (Xantheose), Caffeine, Aspartame (APM) (NutraSweet) and Zidovudine (ZDV) [Azidothymidine (AZT)] as anti–cancer Nano drugs by coassembly of dual anti–cancer Nano drugs to inhibit DNA/RNA of human cancer cells drug resistance.

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Ultraviolet Photoelectron Spectroscopy(UPS) and Ultraviolet–Visible (UV–Vis) Spectroscopy Comparative Study onMalignant and Benign Human Cancer Cells and Tissues with the Passage of Time underSynchrotron Radiation.

Alireza Heidari and Ricardo Gobato. Parana J. Sci. Educ., v.4, n.6, (18-33), August 9, 2018.

DOI: doi.org/10.5281/zenodo.3843560

Abstract

In the current study, we have experimentally and comparatively investigated and compared malignant human cancer cells and tissues before and after irradiating of synchrotron radiation using Ultraviolet Photoelectron Spectroscopy (UPS) and Ultraviolet–Visible (UV–Vis) Spectroscopy.

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Facile synthesis of some oxazepine-steroid using three component system.

Maria Lopez Ramos, Lauro Figueroa Valverde, Francisco Diaz Cedillo, Marcela Rosas Nexticapa, María Virginia del Socorro Mateu Armand, Elizabeth Montano Tapia, Elodia García Cervera, Pool Gómez Eduardo, Lenin Hau Heredia, Regina Cauich Carrillo, Alondra Alfonso Jimenez, Jhair Cabrera Tuz.

Parana J. Sci. Educ., v.4, n.6, (34-45), August 21, 2018.

DOI: doi.org/10.5281/zenodo.3843570

Abstract

There is a great interest in the development of several oxazepine derivatives in both pharmacy and organic chemistry fields such as antidepressant (amoxapine) and schizophrenia (loxapine). In search of new oxazepine analogs some methods use several reagents; however, some of these reagents are expensive and require special conditions for their handling. Therefore, the aim of this study was synthesizing some oxazepine-steroid using three component system (steroid, acetonitrile derivatives and 5-hexyn-1-ol). The chemical structure a purity of compounds was confirmed by melting point, infrared spectra, NMR spectroscopic data and mass spectrometry. The results shown the following; 1) the reagents used for the preparation of oxazepine derivatives does not require special conditions and are facile of handling; 2) the yielding of oxazepine derivatives are relatively good. All these data indicate that production of oxazepine derivatives could be carried out on a larger scale.

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First–Time Simulation of Deoxyuridine Monophosphate (dUMP) (Deoxyuridylic Acid or Deoxyuridylate) and Vomitoxin (Deoxynivalenol (DON)) ((3α,7α)–3,7,15–Trihydroxy–12,13–Epoxytrichothec–9–En–8–One)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations.

Alireza Heidari and Ricardo Gobato. Parana J. Sci. Educ., v.4, n.6, (46-67), August 21, 2018.

DOI: doi.org/10.5281/zenodo.3843580

Abstract

In the current study, Deoxyuridine Monophosphate (dUMP) (Deoxyuridylic Acid or Deoxyuridylate) and Vomitoxin (Deoxynivalenol (DON)) ((3α,7α)–3,7,15–Trihydroxy–12,13–Epoxytrichothec–9–En–8–One) – Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano molecules incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations were studied.

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Parana Journal of Science and Education ISSN 2447-6153