v.4 n.8 November

Parana Journal of Science and Education. v.4, n.8, November (2018).

Summary

Clarification of “Overall Relativistic Energy” According to Yarman’s Approach.

Ozan Yarman, Metin Arik, Ricardo Gobato, Tolga Yarman. Parana J. Sci. Educ., v.4, n.8, (1-10), November 5, 2018.

DOI: doi.org/10.5281/zenodo.3865960

Abstract

In this essay, we will attempt to clarify the concept of “overall relativistic energy” according to Yarman’s Approach; which happens to be the underlying framework of Yarman-Arik-Kholmetskii (YARK) gravitation theory. The reformed meaning of this key concept is, in juxtaposition to the general theory of relativity (GTR), shown to subtly differ from particularly the Newtonian understanding of the “total energy of a system” as just being the “sum of constituent kinetic and potential energies”.

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Abstract

There was proposed the method of near-electrode potential measurement by way of current interruption. To obtain experimental data, a specially designed device was used. With the help of this device, we managed to measure with sufficient accuracy the true potential of the electric double layer and the degree of its change. The measurement results are given for aqueous solutions of univalent and bivalent metal salts.

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Social Stigma of Single University Mothers.

Rosa María Huerta Mata. Parana J. Sci. Educ., v.4, n.8, (17-27), November 16, 2018.

DOI: doi.org/10.5281/zenodo.3865988

Abstract

The objective of this paper is to analyze the capacity of agency and the reflexivity that unmarried university mothers have about the stigmas that surround their motherhood are built in the Faculty of Chemical Science of the Autonomous University of San Luis Potosi (UASLP). This investigation is qualitative in nature. The methodology of life anecdotes through semi-structured individual interviews was used. It took place from February to May in the year 2014; the life anecdotes of 8 students with bachelors in the Faculty of Chemical Science were collected and analyzed; as well as 14 in depth interviews with professors, administrative and staff members. Parting from experience and reflection, they try to establish actions that in some cases, allows them to reach a level of autonomy to restate the stigmas, through lacking efforts of collective work and of elaborated ideas in respect to their sexual and reproductive rights that are directed about more structured demands. It is essential that young women organize themselves as a collective to demand their rights as mothers and students in the area of exact sciences and technologies. Likewise, the UASLP must assume the responsibility of generating changes in the stigmas, as well as, of supporting the permanence of the single mothers in the university.

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Theoretical analysis of biological activity of a new oxocin-steroid derivative against aromatase enzyme using a docking model.

Maria Lopez Ramos, Lauro Figueroa Valverde, Francisco Diaz Cedillo, Abelardo Camacho Luis, Marcela Rosas Nexticapa, María Virginia del Socorro Mateu Armand, Elodia García Cervera, Eduardo Pool Gómez, Lenin Hau Heredia, Alfonso Jimenez Alondra, Jhair Cabrera Tuz.

Parana J. Sci. Educ., v.4, n.8, (28-41), November 23, 2018.

DOI: doi.org/10.5281/zenodo.3866101

Abstract

Several aromatase inhibitors have been prepared for treatment of breast cancer; however, the site of interaction with enzyme surface is not very clear. Therefore, the objective of this investigation was to synthesize and analyze the theoretical activity of a new oxocin-steroid derivative against aromatase (2dw3 protein) in a docking model using some aromatase antagonist (anastrozole and exemestane) as controls. In addition, physicochemical some parameters were determinate such as the inhibition constant (Ki). The results showed that only some of these aminoacid residues involved the surface of the 2dw3 protein may participate in the interaction with anastrozole, exemestane and compound 6. In addition, Ki value was low for exemestane compared with anastrozole and compound 6; however, this physicochemical parameter was similar to both anastrozole and compound 6. All these data suggest that compound 6 could be a good candidate as an aromatase inhibitor which translates as a possible drug for breast cancer.

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Parana Journal of Science and Education. ISSN 2447-6153