18.01.4.5 Lincosamides

An example of a lincosamide is clindamycin. Clindamycin has two mechanisms of actions; it inhibits both bacterial transpeptidation and translocation. Clindamycin is active against Gram-positive cocci, including many penicillin-resistant staphylococci and many anaerobic bacteria. One of the main uses of clindamycin is, oral or topically, for the treatment of any bacterial infection associated with acne.