17.03.4 Muscarinic Receptor Antagonist

Ipratropium bromide is the antimuscarinic agent used in the treatment of rhinorrhea. It is used in the form of a nasal spray. In the nose, ipratropium dries up the nasal secretions. The highest concentrations of ipratropium are in the nose, and there is limited absorption, and a low incidence of adverse effects with this route of administration.