18. Anti-Infectives

Sheila A Doggrell1, Rinku Tuli1 and Elizabeth Davis2

  1. Discipline of Medical Sciences, Faculty of Science and Technology, Queensland University of Technology, Gardens Point, GPO Box 2434, QLD 4001, Australia

Phone +61 7 38705741 Fax +61 7 31381534 Email sheila.doggrell@qut.edu.au

  1. Department of Pharmacology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Melbourne, Australia

Key words: antibiotics, β-lactams, penicillins, cephalosporins, benzylpenicillin, amoxycillin, clavulanic acid, fluocloxacillin, cephalexin, cefotaxime, cefepime, imipenem, glycopeptides, vancomycin, tetracyclines, doxycycline, aminoglycosides, gentamicin, neomycin, chloramphenicol. Macrolides, erythromycin, lincosamides, clindamycin, oxalazidones, linezolid, trimethoprim, anti-tubercuotic, isoniazid, ethambutol, rifamycin, pyrazinamide, anti-viral, aciclovir, zanamivir, oseltamivir, zidovudine, nevirapine, ritonavir, enfuvirtide, anti-fungal, amphotericin, casofungin, fluconazole, terbinafine, griseofulvin

Contents

18.1 Antibiotics

18.1.1 Introduction to bacteria

18.1.2 Introduction to antibiotics

18.1.3 Inhibitors of bacterial cell wall synthesis

18.1.3.1 β-Lactams

18.1.3.2 Glycopeptides

18.1.4 Inhibitors of bacterial protein synthesis

18.1.4.1 Tetracyclines

18.1.4.2 Aminoglycosides

18.1.4.3 Chloramphenicol

18.1.4.4 Macrolides

18.1.4.5 Lincosamides

18.1.4.6 Oxalazidones

18.1.5 Inhibitors of DNA synthesis

18.2. Anti-tuberculotic drugs

18.2.1 Introduction

18.2.2 Isoniazid

18.2.3 Ethambutol

18.2.4 Rifamycin

18.2.5 Pyrazinamide

18.3. Anti-viral drugs

18.3.1 Introduction to viruses

18.3.2 Drugs used to treat herpesviruses

18.3.3 Drugs used to treat the flu

18.3.4 Drugs used to treat HIV/AIDS

18.4. Antifungal drugs

18.4.1 Introduction to Fungi

18.4.2 Antifungal drugs

In this section, the anti-infectives considered are the antibiotics, including anti-tuberculotic drugs, the anti-viral drugs, and the anti-fungal drugs.