Selenium and Miscarriage100% of previously infertile women gave birth after selenium and magnesium supplementationAfter a further two months of 200
micrograms daily oral selenium as selenomethionine and oral magnesium
supplements, all six women normalized their red blood cell magnesium and glutathione peroxidase levels. All 12 previously infertile women
have produced normal healthy babies all conceiving within eight months
of normalizing their magnesium levels.
http://www.ncbi.nlm.nih.gov/pubmed/8054261 Magnesium and Miscarriage Low selenium associated with repeat miscarriageIn recent years selenium deficiency in humans has been
implicated as a risk factor for recurrent miscarriage. The present pilot study from India has
evaluated selenium status in red cells (as they are the better
indicators of selenium levels) in 20 women with three or more
unexplained recurrent miscarriages compared to similar number of
controls. The mean+/-SD red cell selenium levels in the study group was
found to be 119.55 ng/ml, which was
significantly lower compared to the control group with a mean of
150.85 ng/ml. Since selenium
supplementation resulted in successful pregnancy outcome in veterinary
practice, we conclude that large randomised studies are needed to assess
the contribution of selenium in the aetiology of recurrent miscarriage and the potential
benefits of its supplementation.
http://informahealthcare.com/doi/pdf/10.1080/01443610120113373 Two studies found low selenium in women with recurrent miscarriageRecurrent early miscarriage has been associated with reduced serum selenium concentrations compared to healthy controls in two observational studies from UK (54![]() ![]() ![]() Selenium levels in women with recurrent miscarriage were similar to controlsThe mean selenium concentration for women with a history of unexplained
recurrent miscarriage was 67.7 microg/L (SD 16.4). The selenium level
for the women with no history of recurrent miscarriage was 70.3 microg/L
(SD 12.7). There was no difference in selenium concentrations between
the two groups.
http://www.ncbi.nlm.nih.gov/pubmed/10549965 Selenium levels in women who miscarried did not differ from women with continuing pregnancyThe selenium concentrations in whole blood and plasma of women following miscarriage were the same as in viable pregnancy, but were significantly
lower compared with controls.
http://www.ncbi.nlm.nih.gov/pubmed/11281462 Selenium and HormonesSelenium supplementation increases progesteroneSelenium supplementation did not affect the length of the estrous cycle, but
it did increase the concentration of plasma progesterone in the estrous
cycle . These results suggest the possibility that selenium
contributes to the progesterone production of corpus luteum.
http://www.ncbi.nlm.nih.gov/pubmed/9492375 Selenium and ThyroidSelenium added to thyroxidine therapy led to reduced antibody levelsSelenium
supplementation (50-100 microg/day) and thyroxidine therapy resulted in
an increase in plasma glutathione peroxidase (GPX3) by 21%.
Anti-thyroid peroxidase antibody levels decreased by 76%.
http://cat.inist.fr/?aModele=afficheN&cpsidt=20987744 Thyroid and Miscarriage 200 mcg selenium reduced thyroid antibodies by 21%Selenium
supplementation (200 microg/day) resulted in significant reduction of
serum anti-TPO levels during the first 6 months (by 5.6% and 9.9% at 3
and 6 months, respectively). An overall reduction of 21%
was seen after 1 year.
http://www.ncbi.nlm.nih.gov/pubmed/17696828 200 mcg selenium during pregnancy prevented hypothyroidism
Postpartum
thyroid dysfunction and permanent hypothyroidism were significantly
lower in the group that received 200 microg/d throughout pregnancy and
the postpartum period compared with placebo (28.6 vs. 48.6%;
and 11.7 vs. 20.3%).
http://www.ncbi.nlm.nih.gov/pubmed/17284630 Selenium reduces inflammatory cytokines in autoimmune thyroid patientsOur objective was to compare the effect of selenomethionine (organic form of selenium available over the counter) on monocyte and lymphocyte cytokine release and systemic inflammation in patients with Hashimoto's thyroiditis. Selenomethionine inhibited lymphocyte release of IL-2, interferon-γ, and TNF-α, which was accompanied by a reduction in plasma C Reactive Protein levels. CONCLUSIONS: Selenomethionine exhibits a systemic antiinflammatory effect in euthyroid females with Hashimoto's thyroiditis. This action, which correlates with a reduction in thyroid peroxidase antibody titers, may be associated with clinical benefits in the prevention and management of Hashimoto's thyroiditis, particularly in subjects receiving both agents.
http://www.ncbi.nlm.nih.gov/pubmed/21508145 Selenium Daily Upper Limit300 mcg/day selenium is toxicIt
has been shown that dietary intake of about 300 micro g of selenium
daily may have a toxic effect on growth hormone and insulin like growth
factor-1 metabolism, as well as in the synthesis of thyroid hormones.
http://www.ncbi.nlm.nih.gov/pubmed/17160166 Other topics covered under Vitamins:
Biotin, Calcium, Choline, Chromium, Folic Acid, Magnesium, Multivitamins, Phosphorus, Selenium, Vitamin A, Vitamin B12, Vitamin B6, Vitamin C, Vitamin D, Vitamin E, Vitamin K, Zinc |