Insulin resistance seems to be one of the major causes of obesity-related complications due to increased secretion of TNF-alpha, IL-6 and C-reactive protein together with android obesity.
http://www.bratislleklisty.sk/2010/11104-05.pdf
Hyperglycemia is associated with heart arrythmias and recurrent infections.
Hyperglycemia can occur naturally at times of infection or inflammation.
When there is extra glucose in blood, one way the body gets rid of it is through frequent urination.