Post date: Mar 9, 2016 7:38:28 AM
Dr. Eunjin Kim's Nature Medicine paper is published online on April 18.
"GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice"
Hyejung Won, Won Mah, Eunjin Kim, Jae-Won Kim, Eun-Kyoung Hahm, Myoung-Hwan Kim, Sukhee Cho, Jeongjin Kim, Hyeran Jang, Soo-Churl Cho, Boong-Nyun Kim, Min-Sup Shin, Jinsoo Seo, Jaeseung Jeong, Se-Young Choi, Daesoo Kim, Changwon Kang & Eunjoon Kim
Published online: 17 April 2011 | doi:10.1038/nm.2330
ADHD is characterized by hyperactivity and deficits in learning and memory. Now, Eunjoon Kim and colleagues report that a polymorphism in the gene that encodes the adaptor protein GIT1 is linked to ADHD in humans. This polymorphism reduces GIT1 expression, and GIT1-deficient mice show ADHD-like behaviors that can be alleviated with the psychostimulant drugs used to treat human ADHD.
Abstract - | Full Text - GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice | PDF (1,601 KB) - GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice | Supplementary information
Prof. Kang had an interview with KBS-TV, MBC-TV, YTN-TV, and TJB-TV in the morning on April 18.