Genetics Call 2017-02-27

Post date: Feb 27, 2017 5:02:53 PM

1. Project updates

a. Integrative genomics: submitted (Bosse)

b. Emphysema: in progress.  All primary analyses complete from COPDGene Nhw, COPDGene Aa, GenKOLS, ECLIPSE, FHS, MESA Nhw, MESA Aa, Mesa Chinese.  Need to clarify HRC and secondary analyses.  Re-contact other studies.

c. Case control: UK biobank access approved.  Discussion about the role of biobanks -- Beaty, Hobbs, Busch, all commented -- is an important source especially going forward, consider symptom-directed, overlap with other signals, role of exacerbations.

d. GxE occupation interaction (Boezen)

2. New projects

a. sQTL (Hersh / Saferali): using leafcutter.

May be helpful to post a list of approved studies.

3. Administrative issues

Will need to cancel April call d/t travel / boards.

Plan to schedule a Washington DC ATS event.