Genetics Call 2015-4-27
Post date: Apr 27, 2015 3:18:14 PM
1. Case control analysis updates:
Currently: ARIC, B58C, COPACETIC, COPDGene NHW, COPDGene AA, ECLIPSE, eQTL, Framingham, KARE, Lifelines, LHS, MESA, NETT-NAS, Norway (GenKOLS), Rotterdam.
Pending: CHS, Lovelace, SPIROMICS.Â
Using EasyQC (from GIANT), and will share with Marike and Kim to do a parallel meta-analysis through Syncplicity.
Not all studies are submitting all analyses, also variable who submits an X chromosome analysis - will need to be addressed.
2.Emphysema analysis: draft analysis plan circulated: participating cohorts currently: BWH Lung tissue, COPACETIC/NELSON, COPDGene, ECLIPSE, Framingham, GenKOLS, MESA, NETT, Rotterdam, SPIROMICS, TESRA.
Note that these will also likely require using pre-bronchodilator FEV1.
3. ICGC Genetics grant resubmission planned for this fall.