Genetics Call 2015-6-19

Post date: Jun 29, 2015 3:36:40 PM

1. Case control analysis updates:

Have received CHS, Lovelace.  Have not received SPIROMICS, will re-contact.

EasyQC has identified several QC issues, in contact with individual studies to troubleshoot; hopefully over the next few weeks.

Lovelace results not imputed; the UMich Imputation Server may be helpful to get this done more quickly.

Clarified that baseline characteristics (mean / sd or %) should include all covariates and outcomes used in the analyses.

2.Emphysema analysis - ongoing discussions.  Challenges with cases having different distribution from population based cohorts.

3. ICGC Genetics grant resubmission planned for this fall.  Need more innovative, novel analyses rather than just power.