Trianthema portulacastrum

Generalidades

Sinónimos: No aplican.

Nombre común: Verdolaga, verdolaga blanca, verdolaga del burro (en la zona). Guilanche, verdolaga bronca (fuea de la zona).

Características generales:

  • Es una planta generalmente rastrera, algo suculenta, con hojas opuestas, pero desiguales, anchas y emarginadas, con flores blancas a rosadas de aproximadamente 1 cm.

  • Su fruto en forma de cápsula algo curva de 4-5 mm de largo con apertura circuncísil (abriendo en círculo) con pocas semillas;

  • Sus semillas de contorno en forma de corazón, raras veces triangular u ovado deprimido, en forma de espiral, de (1.3)1.8 (2.3) mm de largo y (1.1) 1.6 (2.1) mm de ancho; comprimidas, de color café o café grisáceo a negro brillante, tuberculadas

  • Sus flores son parcialmente envueltas por la base ensanchada y membranosa del pecíolo; tépalos lanceolados, de 4-5 mm de largo, morados o rojizo-morados por dentro, con un apéndice exterior cerca del ápice. Ovario con 1 o 2 estilos y lóculos; estambres generalmente 5-10.

Usos medicinales reportados

  • Usada principalmente como un analgésico natural.

  • Usado para obtener efectos relajantes en las vías respiratorias.

  • Utilizado como remedio para tratar la artritis.

  • Es utilizado como un laxante natural.

  • Utilizado para reforzar el sistema inmune gracias a sus propiedades.

Usos farmacológicos reportados

  • Efectos antinociceptivos

  • Efectos antiartríticos

  • Efecto terapéutico

  • Efectos protectores

  • Efectos procineticos

  • Efectos laxantes

  • Efecto gastroprotector

  • Efecto relajante en las vías respiratorias

  • Efectos protectores y terapéuticos

  • Actividad analgésica

  • Respuestas antiinflamatorias

  • Eliminador de estrés

  • Potencial antimicrobiano

  • Actividad fitotoxica

  • Micronutrientes

Bibliografías

Biblioteca virtual UAQ

  1. Biblioteca digital de la Herbolaria Mexicana UNAM


PubMed

  1. Wu H, Gao T, Cao Y, Diao J, Chang F, Qi J, Wang C. Protective and therapeutic effects of Trianthema portulacastrum against atherosclerosis in male albino rats via G-protein-coupled receptor 124. AMB Express. 2019 Oct 31;9(1):178. doi: 10.1186/s13568-019-0901-7. PMID: 31673813; PMCID: PMC6823334.

  2. Mandal A, Bishayee A. Trianthema portulacastrum Linn. displays anti-inflammatory responses during chemically induced rat mammary tumorigenesis through simultaneous and differential regulation of NF-κB and Nrf2 signaling pathways. Int J Mol Sci. 2015 Jan 22;16(2):2426-45. doi: 10.3390/ijms16022426. PMID: 25622256; PMCID: PMC4346844.

  3. Falade T, Ishola IO, Akinleye MO, Oladimeji-Salami JA, Adeyemi OO. Antinociceptive and anti-arthritic effects of aqueous whole plant extract of Trianthema portulacastrum in rodents: Possible mechanisms of action. J Ethnopharmacol. 2019 Jun 28;238:111831. doi: 10.1016/j.jep.2019.111831. Epub 2019 Mar 28. PMID: 30930256.

  4. Yadav E, Singh D, Yadav P, Verma A. Attenuation of dermal wounds via downregulating oxidative stress and inflammatory markers by protocatechuic acid rich n-butanol fraction of Trianthema portulacastrum Linn. in wistar albino rats. Biomed Pharmacother. 2017 Dec;96:86-97. doi: 10.1016/j.biopha.2017.09.125. Epub 2017 Sep 29. PMID: 28965012.

  5. Zihad SMNK, Gupt Y, Uddin SJ, Islam MT, Alam MR, Aziz S, Hossain M, Shilpi JA, Nahar L, Sarker SD. Nutritional value, micronutrient and antioxidant capacity of some green leafy vegetables commonly used by southern coastal people of Bangladesh. Heliyon. 2019 Nov 19;5(11):e02768. doi: 10.1016/j.heliyon.2019.e02768. PMID: 31768435; PMCID: PMC6872803.


Google Scholar

  1. Sukalingam, K., Ganesan, K. & Xu, B. Trianthema portulacastrum L. (giant pigweed): phytochemistry and pharmacological properties. Phytochem Rev 16, 461–478 (2017). https://doi.org/10.1007/s11101-017-9493-5

  2. Yadav, E., Singh, D., Yadav, P., & Verma, A. (2018). Ameliorative effect of biofabricated ZnO nanoparticles of Trianthema portulacastrum Linn. on dermal wounds via removal of oxidative stress and inflammation. RSC Advances, 8(38), 21621–21635. doi:10.1039/c8ra03500h 

  3. Falade, T., Ishola, I. O., Akinleye, M. O., Oladimeji-Salami, J. A., & Adeyemi, O. O. (2019). Antinociceptive and anti-arthritic effects of aqueous whole plant extract of Trianthema portulacastrum in rodents: Possible mechanisms of action. Journal of Ethnopharmacology, 111831. doi:10.1016/j.jep.2019.111831 

  4. Abd El-Gawad, A. M., El Gendy, A. G., Elshamy, A. I., & Omer, E. A. (2016). Chemical Composition of the Essential Oil of Trianthema portulacastrum L. Aerial Parts and Potential Antimicrobial and Phytotoxic Activities of its Extract. Journal of Essential Oil Bearing Plants, 19(7), 1684–1692. doi:10.1080/0972060x.2016.1205523 

  5. Yadav, E., Singh, D., Debnath, B. et al. Molecular Docking and Cognitive Impairment Attenuating Effect of Phenolic Compound Rich Fraction of Trianthema portulacastrum in Scopolamine Induced Alzheimer’s Disease Like Condition. Neurochem Res 44, 1665–1677 (2019). https://doi.org/10.1007/s11064-019-02792-7

  6. Mandal, A., & Bishayee, A. (2015). Trianthema portulacastrum Linn. Displays Anti-Inflammatory Responses during Chemically Induced Rat Mammary Tumorigenesis through Simultaneous and Differential Regulation of NF-κB and Nrf2 Signaling Pathways. International Journal of Molecular Sciences, 16(2), 2426–2445. doi:10.3390/ijms16022426 

  7. Yadav, E., Singh, D., Yadav, P., & Verma, A. (2017). Attenuation of dermal wounds via downregulating oxidative stress and inflammatory markers by protocatechuic acid rich n -butanol fraction of Trianthema portulacastrum Linn. in wistar albino rats. Biomedicine & Pharmacotherapy, 96, 86–97. doi:10.1016/j.biopha.2017.09.125 

  8. Jabbar, A., Sirajuddin, M., Iqbal, S., Tariq, M. I., & Ahmad, M. (2019). Exploration of Antioxidant Activities of Potentially Bioactive Compounds in Trianthema portulacastrum Herb: Chemical Identification and Quantification by GC-MS and HPLC. ChemistrySelect, 4(3), 925–935. doi:10.1002/slct.201803267 

  9. Kendri, Suresh S., and Umesh G. Wari. "Screening of the antiinflammatory activity of 'trianthema portulacastrum' in acute models of inflammation." Journal of Evolution of Medical and Dental Sciences, vol. 4, no. 30, 13 Apr. 2015, pp. 5185+. Accessed 21 Sept. 2021.

  10. Moawad, Abeer & Abuzaid, Hala & Arafa, Waleed & Ahmed, Osama & Hetta, Mona & Mohammad, Rabab. (2020). Anticholinesterase and acaricidal activities of steroids isolated from Trianthema portulacastrum L. against Rhipicephalus annulatus tick. Journal of Applied Pharmaceutical Science. 10. 47-55. 10.7324/JAPS.2020.104008.

  11. Wu, H., Gao, T., Cao, Y. et al. Protective and therapeutic effects of Trianthema portulacastrum against atherosclerosis in male albino rats via G-protein-coupled receptor 124. AMB Expr 9, 178 (2019). https://doi.org/10.1186/s13568-019-0901-7

  12. Sukalingam, Kumeshini & Ganesan, Kumar & Ponnusamy, Kumar. (2015). Pharmacological properties of Trianthema portulacastrum L and its therapeutic potential as Complementary Medicine.. 4. 2015.

  13. Bashir, Samra & Abbas, Saima & Khan, Aslam. (2018). Pharmacological studies on prokinetic and laxative effects of trianthema portulacastrum linn. International Journal of Complementary & Alternative Medicine. 11. 10.15406/ijcam.2018.11.00428.

  14. Prakash A, Janmeda P, Sharma V. Bioactivity and Pharmacological Potential of Trianthema portulacastrum L. (Angiosperms: Aizoaceae): An Overview. Plant Sci. Today [Internet]. 2019 Dec. 31 [cited 2021 Sep. 21];6(sp1):590-9. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/678

  15. Yadav, E. (2019).Protective effect of protocatechuic acid rich fraction of trianthema portulacastrum against collagen induced rheumatoid arthritis via gut microbiota modulation.doi:10.1136/annrheumdis-2019-eular.2530 

  16. Bashir, S., Abbas, S., Mandukhail, S., & Hassan Gilani, A. (2018). The Airway Relaxant Effect of Horse Purslane, Trianthema portulacastrum, Linn. (Aizoaceae), is Mediated through Dual Blockade of Muscarinic Receptors and Ca2+ Influx. Journal of Pharmaceutical Research International, 23(6), 1-9. https://doi.org/10.9734/JPRI/2018/44409

  17. Wari, Umesh G. "Analgesic activity of ethanolic extract of the plant trianthema portulacastrum in experimental models." Journal of Evolution of Medical and Dental Sciences, vol. 4, no. 34, 27 Apr. 2015, pp. 5867+. Accessed 21 Sept. 2021.


ScienceDirect

  1. Falade, T., Ishola, I. O., Akinleye, M. O., Oladimeji-Salami, J. A., & Adeyemi, O. O. (2019). Antinociceptive and anti-arthritic effects of aqueous whole plant extract of Trianthema portulacastrum in rodents: Possible mechanisms of action. Journal of Ethnopharmacology, 111831. doi:10.1016/j.jep.2019.111831 

  2. Yadav, P. (2019). Molecular docking studies and cognitive impairment attenuating effect of phenolic compound rich fraction of trianthema portulacastrum in scopolamine induced Alzheimer’s disease like condition. Journal of the Neurological Sciences, 405, 36. doi:10.1016/j.jns.2019.10.833

  3. Gutti, U., Pasupuleti, S. R., Sahu, I., Kotipalli, A., Undi, R. B., Kandi, R., … Gutti, R. K. (2016). Erythropoietin and thrombopoietin mimetics: Natural alternatives to erythrocyte and platelet disorders. Critical Reviews in Oncology/Hematology, 108, 175–186. doi:10.1016/j.critrevonc.2016.11.002 

  4. Rajeshkumar, S., & Bharath, L. V. (2017). Mechanism of plant-mediated synthesis of silver nanoparticles – A review on biomolecules involved, characterisation and antibacterial activity. Chemico-Biological Interactions, 273, 219–227. doi:10.1016/j.cbi.2017.06.019 


BioMed Research International

  1. Mummed, B., Abraha, A., Feyera, T., Nigusse, A., & Assefa, S. (2018). In Vitro Antibacterial Activity of Selected Medicinal Plants in the Traditional Treatment of Skin and Wound Infections in Eastern Ethiopia. BioMed Research International, 2018, 1–8. doi:10.1155/2018/1862401 

  2. Huang, F., Long, Y., Liang, Q., Purushotham, B., Swamy, M. K., & Duan, Y. (2019). Safed Musli (Chlorophytum borivilianum L.) Callus-Mediated Biosynthesis of Silver Nanoparticles and Evaluation of their Antimicrobial Activity and Cytotoxicity against Human Colon Cancer Cells. Journal of Nanomaterials, 2019, 1–8. doi:10.1155/2019/2418785 

  3. Jemal, K., Sandeep, B. V., & Pola, S. (2017). Synthesis, Characterization, and Evaluation of the Antibacterial Activity ofAllophylus serratusLeaf and Leaf Derived Callus Extracts Mediated Silver Nanoparticles. Journal of Nanomaterials, 2017, 1–11. doi:10.1155/2017/4213275 

  4. Firdhouse, M. J., & Lalitha, P. (2015). Biosynthesis of Silver Nanoparticles and Its Applications. Journal of Nanotechnology, 2015, 1–18. doi:10.1155/2015/829526 

Springer Link

  1. Wu, H., Gao, T., Cao, Y. et al. Protective and therapeutic effects of Trianthema portulacastrum against atherosclerosis in male albino rats via G-protein-coupled receptor 124. AMB Expr 9, 178 (2019). https://doi.org/10.1186/s13568-019-0901-7

  2. Sharmila Banu, G., Kumar, G. & Murugesan, A.G. Effect of ethanolic leaf extract of Trianthema portulacastrum L. On aflatoxin induced hepatic damage in rats. Indian J Clin Biochem 24, 414 (2009). https://doi.org/10.1007/s12291-009-0074-2

  3. Mandal, A., Karmakar, R., Bandyopadhyay, S. et al. Antihepatotoxic potential ofTrianthema portulacastrum in carbon tetrachloride-induced chronic hepatocellular injury in mice: Reflection in haematological, histological and biochemical characteristics. Arch. Pharm. Res. 21, 223 (1998). https://doi.org/10.1007/BF02975279

  4. Sharmila Banu, G., Kumar, G. & Murugesan, A.G. Ethanolic leaves extract of Trianthema portulacastrum L. ameliorates aflatoxin B1 induced hepatic damage in rats. Indian J Clin Biochem 24, 250–256 (2009). https://doi.org/10.1007/s12291-009-0047-5