Klebsiella pneumoniae Infection from World Championship in Medical Science
According to World Championship in Medical Science,Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis.
Klebsiella is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. Increasingly, Klebsiella bacteria have developed antimicrobial resistance, most recently to the class of antibiotics known as carbapenems. Klebsiella bacteria are normally found in the human intestines (where they do not cause disease). They are also found in human stool (feces). In healthcare settings, Klebsiella infections commonly occur among sick patients who are receiving treatment for other conditions. Patients whose care requires devices like ventilators (breathing machines) or intravenous (vein) catheters, and patients who are taking long courses of certain antibiotics are most at risk for Klebsiella infections. Healthy people usually do not get Klebsiella infections.
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Symptoms of Klebsiella pneumoniae Infection
Symptoms of Klebsiella pneumoniae Infection include
-a cough with thick yellow, green, or blood-tinged mucus.
-stabbing chest pain that worsens when coughing or breathing.
-sudden onset of chills severe enough to make you shake.
-fever of 102-105°F or above (fever lower than 102°F in older persons)
Diagnosis of Klebsiella pneumonia infection
Diagnosis of isolates harbouring carbapenemases can be inconsistent using automated systems, often requiring subsequent confirmatory tests. Phenotypic methods utilizing boronic acid disc tests have demonstrated promising results and appear practical for use in clinical microbiology laboratories.
Treatment of Klebsiella pneumonia infection
Klebsiella infections that are not drug-resistant can be treated with antibiotics. Infections caused by KPC-producing bacteria can be difficult to treat because fewer antibiotics are effective against them. Other antibiotics used to treat susceptible isolates include ampicillin/sulbactam, piperacillin/tazobactam, ticarcillin/clavulanate, ceftazidime, cefepime, levofloxacin, norfloxacin, moxifloxacin, meropenem, and ertapenem. Treatment of Klebsiella pneumonia has discrepant results.
Statistics of Klebsiella pneumonia infection
In 2012, the EU/EEA population-weighted mean percentage of K. pneumoniae isolates resistant to third-generation cephalosporins was 25.6%, with national percentages ranging from 1.7% (Finland) to 74.8% (Bulgaria).
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