Aucott, John N.
John N. Aucott
Johns Hopkins
From his slide presentation...
Hypothesis for Pathophysiology of PTLDS
- “Hum” of general population
- Triggered anxiety or depression
- Susceptibility from traumatic life events
- Autoimmune
- Anti-neural antibodies
- Dependent or independent on bacterial products
- Post-infectious syndromes of arthritis, fatigue
- Persistent damage
- Campylobacter-triggered reactive arthritis, post-infectious fatigue
- Persistent post-treatment infection
- Q fever, brucellosis
One Slide from Power Point Presentation by Aucott- Link Here To Download Program
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Another Slide by Aucott
Take-Home Points
- Post-treatment Lyme Disease Syndrome is a potential long term complication of Lyme disease.
- Patients who are self-identified as having Chronic Lyme Disease need a thorough diagnostic evaluation including a detailed history to identify those with PTLDS
- There is evidence that depression is not the “cause” of symptom persistence in PTLDS
- After an extensive evaluation many patients will have Medically Unexplained Symptoms or may fit a syndrome such as fibromyalgia or Chronic Fatigue
- PTLDS presents opportunity to model symptom based syndromes
- models incorporate both biologic and behavioral variables that interact to determine patient’s phenotype
- Biomarkers for diagnosis and monitoring of Post Treatment Lyme Syndrome are urgently needed
Refers to himself as LymeMd along with others who ARE Lyme literate treating doctors.
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Aucott- $10 Million Grant
November 8, 2016
Johns Hopkins University received a $10 million grant from the Steven and Alexandra Cohen Foundation to explore Lyme disease and develop potential new therapies to address the illness. Johns Hopkins is the only institution in the nation to receive multiple Lyme disease grants from the foundation.
The grant will be divided among three Johns Hopkins research teams led by John Aucott, M.D.; Ying Zhang, M.D., Ph.D.; and Brian Schwartz, M.D.
Link To Article Here