Typically state and county health departments promote the IDSA and CDC's information regarding Lyme and tick borne diseases, be it right or wrong that is their job. As a result countless people have not been properly diagnosed or treated for serious infectious diseases that can cause severe acute illness, disability and/or death.
Still today doctors are telling people there is no Lyme disease in Florida, or that a positive test for Lyme must be a false-positive. Not so!
Common misdiagnoses in our Florida Lyme and tick borne disease patients consist of fibromyalgia, MS, depression, Lupus, cancer and arthritis. If you have been diagnosed with any of these conditions or other similar conditions and have any concerns about your diagnosis please seek an independent opinion from a competent Lyme treating doctor. (See Doctor Referrals on the menu to your left.)
As you will note in the literature in this section, the Florida Department of Health promotes the sixteen year old Infectious Diseases Society of America (IDSA) guidelines, almost word-for-word, to the exclusion of alternative view points by other medical organizations. Click here to read the Attorney General's findings regarding the IDSA Lyme disease guidelines. In part it reads:
"The IDSA's 2006 Lyme disease guideline panel undercut its credibility by allowing individuals with financial interests -- in drug companies, Lyme disease diagnostic tests, patents and consulting arrangements with insurance companies -- to exclude divergent medical evidence and opinion."
The Florida Department of Health's Lyme Disease Information
Based on IDSA/CDC Theories
Dr. Lisa Conti, State Public Health Veterinarian
Lyme disease (LD) is caused by the bacterium Borrelia burgdorferi which is transmitted to people (and some animals) through the bite of an infected tick. It takes more than a day of attachment for an infected tick to transmit the bacterium to a new host. Ticks typically become infected after feeding on white-footed mice (Peromyscus leucopus) that have a bacteremia with B. burgdorferi. The tick Ixodes scapularis is implicated as the vector of LD in much of the eastern seaboard. I. scapularis is found throughout Florida.
As a reportable condition in Florida, it is incumbent on practitioners and laboratories to report suspected or diagnosed cases of LD to their respective county health departments. For epidemiologic purposes, the case definition for LD includes both acute and chronic disease manifestations. A documented case of acute LD is contingent upon a physician-diagnosed erythema migrans (EM) lesion that is at least 5 centimeters. In many people, this lesion appears 7 to 10 days (range 3 to 31 days) after being bitten by infected ticks. Annular erythematous lesions arising a few hours after tick attachment are hypersensitivity reactions usually responsive to antihistamines and are not EM.
Because late manifestations of LD can include musculoskeletal, neurologic and/or cardiovascular disease (when alternate etiologies have been ruled out), the case definition requires supportive laboratory findings.1 Some LD laboratory tests may not have consistent quality control and/or are notorious for cross-reacting with other agents.
Therefore, the Association of State and Territorial Public Health Laboratory Directors, the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration, the National Institutes of Health, the Council of State and Territorial Epidemiologists and the National Committee for Laboratory Standards have recommended a two-test approach to LD serodiagnosis.2
First, sera are analyzed using a sensitive enzyme immunoassay (EIA) or an immunofluorescent assay (IFA) for exposure to LD. If positive, sera should be tested by a standardized Western immunoblot algorithm. If the serum is drawn within the first four weeks of disease, both immunoglobulin M (IgM) and immunoglobulin G (IgG) assays should be performed; after 4 weeks, IgG is recommened because a positive IgM alone has a high likelihood for a false-positive test result in such patients.
IgM immunoblot is considered positive with the presence of two of the three bands: 21 kDa (or 24kDa since they both measure OspC), 39kDa and 41 kDa. IgG is considered positive with the presence of five of the 10 bands: 18 kDa, 21 kDa (or 24kDA), 28 kDa, 30 kDa, 39 kDa, 41 kDa, 45 kDa, 58 kDa, 66 kDa, and 93 Kda. Lyme urine antigen tests are not recommended due to the high likelihood of false-positive test results. NOTE: The Florida Department of Health Jacksonville Laboratory offers the EIA with confirmatory testing conducted at the CDC Laboratory (please contact 904-791-1540 for information regarding sample submission.)
In Florida, 315 human cases of Lyme disease were reported during the 20-year period, 1980 through 1999. Two thirds of these cases (209) were reported during the recent 4-year period, 1996 through 1999. Of these 209, 63% had a documented travel history out of the state prior to onset of clinical signs. EM was reported in 56% of the 209 cases. LD does occur in Florida but at a low prevalence compared with other states (notably the northeast).
Borrelia burgdorferi has never been cultured from an EM lesion in the southeast as it has in northeastern states. Genetically different strains of B. burgdorferi have been isolated from cotton rats. Physicians should be aware that some "southern tick-associated rash illness" (STARI) in Florida may be caused by another species of Borellia thought to be vectored byAmbylomma americanum (lone star) ticks.
The Centers for Disease Control and Prevention is asking for physician/patient participation in a study to identify the cause of the red, expanding skin rash that sometimes occurs after a tick bite in people living in the southeastern United States. Requested study samples include skin biopsy specimens from the rash site, and blood and urine specimens.
Some of the samples will be stored until sensitive and specific tests are available to determine the causative agent. Additional information about the CDC STARI study is can be found on the Department of Health Website at the following address: http://www.doh.state.fl.us/disease_ctrl/epi/htopics/popups/lyme.htm.
- Due to similarity of manifestations, physicians may wish to test their patients for reactive arthropathy (Reiter’s syndrome).
- "Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease." MMWR, August 11, 1995/44(31); 590-591.
Lyme Disease in Florida
Florida Department of Health Lyme Disease Webpage- Click Here.