What is a potential benefit of using mirabegron over antimuscarinic medications for treating overactive bladder?

A. Increased risk of dry mouth

B. Reduced risk of cognitive impairment

C. Increased risk of urinary retention

D. Reduced efficacy in treating symptoms

A 48-year-old man with myocardial infarction is started on an ACEI.  He is started on a low dose and the aim is to titrate to the target dose within four weeks. On routine follow up of labs one week from starting the drug, his serum creatinine is increased by 20% from the baseline. What would be the most appropriate action?

 A. Stop the ACEI

 B. Continue titrating the ACEI

 C. Keep the current dose of ACEI

 D. Substitute the ACEI with an ARBs