Drug dose calculation and relevant practice resources
Drug dose calculation and relevant practice resources
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Drug calculations - Ggeeky Medics
Drug Calculation Cases - Ggeeky Medics
Pharmaceutical Calculations Made Easy!
Drug Calculations: How to Use the Universal Formula
Drug Calculations - Flinders University
Pharmacy Calculations - StatPearls
Drug Dosage Calculations - George Brown College
Half-life of a drug (t1/2) calculation
The half-life of a drug (t1/2) is the time required for the drug's concentration in the body to decrease by exactly 50%. It can be calculated using two main formulas depending on the data available:
Volume of Distribution
Vd of drug C was determined to be 20 L. What would be the expected drug plasma concentration immediately after an IV dose of 2 mg is given to a 70 kg male patient?
A. 0.01 mirogram/dL
B. 1 mircrogram/ dL
C. 0.1 microgram/ dL
D. 10 microgram/ dL
Formula: Vd= dose/ Cp
Cp = Do/ Vd
Do = 2000ug
Vd = 20L = 200dL (10dL = 1L)
Cp = 2000/200 = 10 ug/dL
Answer: D. 10 microgram/ dL
Directions for questions 1-30: Each question, statement, or incomplete statement in this section can be correctly answered or completed by one of the suggested answers or phrases. Choose the best answer.
1. If a vitamin solution contains 0.5 mg of fluoride ion in each milliliter, then how many milligrams of fluoride ion would be provided by a dropper that delivers 0.6 mL?
(A) 0.3 mg
(B) 0.1 mg
(C) 1 mg
(D) 0.83 mg
We know, C1V1=C2V2
In this problem, V1=0.5mg; C1=1.0 milliliter; C2=?; V2=0.6mL
C2=C1V1/V2
C2=0.5x1/0.6
2. How many chloramphenicol capsules, each containing 250 mg, are needed to provide 25 mg per kg per day for 7 days for a person weighing 200 lb?
(A) 90 capsules
(B) 64 capsules,
(C) 13 capsules
(D) 25 capsules
We know, C1V1=C2V2
In this problem,
3. If 3.17 kg of a drug is used to make 50,000 tablets, how many milligrams will 30 tablets contain?
(A) 1.9 mg
(B) 1900 mg
(C) 0.0019 mg
(D) 3.2 mg
We know, C1V1=C2V2
In this problem,
4. A capsule contains a gr of ephedrine sulfate, 1½ gr of theophylline, and 16 1/16 gr of phenobar-bital. What is the total mass of the active ingre-dients in milligrams?
(A) 20 mg
(B) 8 mg
(C) 28 mg
(D) 4 mg
We know, C1V1=C2V2
In this problem,
5. If 1 fluid ounce of a cough syrup contains 10 gr of sodium citrate, how many milligrams are contained in 10 mL?
(A) 650 mg
(B) 65 mg
(C) 217 mg
(D) 20 mg
We know, C1V1=C2V2
In this problem,
6. How many capsules, each containing grof phenobarbital, can be manufactured if a bot-tle containing 2 avoirdupois ounces of pheno barbital is available?
(A) 771 capsules
(B) 350 capsules
(C) 3500 capsules
(D) 1250 capsules
We know, C1V1=C2V2
In this problem,
7. Using the formula for calamine lotion, determine the amount of calamine (in grams) necessary to prepare 240 mL of lotion.
Calamine -80 g
Zinc oxide -80 g
Glycerin -20 mL
Bentonite magma -250 ml
Calcium hydroxide -sufficient quantity to make 1000 mL topical solution
(A) 19.2 g
(B 140 g
(C) 100 g
(D) 24 g
We know, C1V1=C2V2
In this problem,
8. From the following formula, calculate the amount of white wax required to make 1 lb of cold cream. Determine the mass in grams.
Cetyl esters wax
12.5 parts
White wax
12.0 parts
Mineral oil
56.0 parts
Sodium borate
0.5 parts
Purified water
19.0 parts
(A) 56.75 g
(B) 254.24 g
(C) 54.48 g
(D) 86.26 g
We know, C1V1=C2V2
In this problem,
9. How many grams of aspirin should be used to prepare 1.255 kg of the powder?
ASA
Phenacetin
6 parts
Caffeine
3 parts
1 part
(A) 125 g
(B) 750 g
(C) 175 g
(D) 360 g
We know, C1V1=C2V2
In this problem,
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