B2 Genetic factors that affect development

Genetic predisposition to particular conditions

1.cystic fibrosis

2.brittle bone disease

3.phenylketonuria (PKU)

4.Huntington’s disease

5.Klinefelter’ssyndrome

6.Down’s syndrome

7.colour blindness

8.Duchenne muscular dystrophy

For each of the above:

1. Explain what the condition is.

2. List symptoms.

3. Explain how it is genetically passed on.

Susceptibility to diseases

1.cancer

2.high blood cholesterol

3.diabetes

For each of the above:

1. Explain what the condition is.

2. Explain how susceptibility is increased by genetics.

Biological factors that affect development

1. foetal alcohol syndrome

2. effects of maternal infections and lifestyle/diet during pregnancy - smoking

3. congenital defects

For each of the above:

1. Explain how each of the above can affect a babies development.

Scenario

George is 65 years old and lives with his wife Polly, who is 53 years old. Their adult daughter, Nita, is 19 years old and has foetal alcohol syndrome.

Exam question

Explain the effects of foetal alcohol syndrome on Nita’s intellectual development. (6 marks)