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Scientists completely sequence human Y chromosome for the first time
By Katie Hunt
Scientists completely sequence the human Y chromosome for the first time
By Katie Hunt
Los científicos lograron secuenciar completamente el cromosoma Y por primera vez. Y como resultado, descubrieron información que podría tener consecuencias en el estudio de la infertilidad masculina y otros problemas de salud.
El primer intento de determinar los componentes básicos de nuestro código genético se produjo hace 20 años, pero aún quedaban lagunas importantes en las secuencias de los 23 pares de cromosomas humanos. El año pasado, un grupo internacional de 100 científicos, el Consorcio Telómero a Telómero (T2T), completó gran parte de esas lagunas.
Sin embargo, más de la mitad de las secuencias del cromosoma Y, el más pequeño y complicado de los 46 cromosomas humanos, seguían siendo desconocidas. Ahora, el mismo grupo de investigadores completó la información que faltaba, publicando este miércoles una secuencia completa del cromosoma Y en la revista académica Nature.
"Hace apenas unos años, faltaba la mitad del cromosoma Y humano", afirma en un comunicado Monika Cechova, coautora principal del artículo y becaria postdoctoral en Ingeniería Biomolecular de la Universidad de California en Santa Cruz.
"Por aquel entonces ni siquiera sabíamos si se podía secuenciar, era tan desconcertante", añadió Cechova. "Esto es realmente un cambio enorme en lo que es posible".
Scientists succeeded in completely sequencing the Y chromosome for the first time. And as a result, they discovered information that could have implications for the study of male infertility and other health problems.
The first attempt to determine the basic components of our genetic code was made 20 years ago, but there were still major gaps in the sequences of the 23 pairs of human chromosomes. Last year, an international group of 100 scientists, the Telomere-to-Telomere (T2T) Consortium, filled in much of those gaps.
However, more than half of the sequences of the Y chromosome, the smallest and most complicated of the 46 human chromosomes, remained unknown. Now, the same group of researchers completed the missing information, publishing this Wednesday a complete sequence of the Y chromosome in the academic journal Nature.
"Just a few years ago, half of the human Y chromosome was missing," Monika Cechova, co-lead author of the paper and a postdoctoral fellow in Biomolecular Engineering at the University of California, Santa Cruz, says in a statement.
"Back then we didn't even know if it could be sequenced, it was so puzzling," Cechova added. "This is really a huge change in what is possible."
Scientists succeeded in completely sequencing the Y chromosome for the first time. And as a result, they discovered information that could have implications for the study of male infertility and other health problems.
The first attempt to determine the basic components of our genetic code occurred 20 years ago, but there were still major gaps in the sequences of the 23 pairs of human chromosomes. Last year, an international group of 100 scientists, the Telomere-to-Telomere (T2T) Consortium, filled in much of those gaps.
However, more than half of the sequences of the Y chromosome, the smallest and most complicated of the 46 human chromosomes, remained unknown. Now, the same group of researchers filled in the missing information, publishing a complete sequence of the Y chromosome Wednesday in the academic journal Nature.
"Just a few years ago, half of the human Y chromosome was missing," Monika Cechova, co-lead author of the paper and a postdoctoral fellow in Biomolecular Engineering at the University of California, Santa Cruz, says in a statement.
"Back then we didn't even know if it could be sequenced, it was so puzzling," Cechova added. "This is really a huge change in what's possible."
Final Version as reviewed by a human translator:
Scientists achieved to complete the Y chromosome for the first time. As a result, they discovered information that could have implications for studying male infertility and other health problems.
The first attempt to determine the basic components of our genetic code was carried out 20 years ago, but there were still major gaps in the sequences of the 23 pairs of human chromosomes. Last year, an international group of 100 scientists from the Telomere-to-Telomere (T2T) Consortium filled in much of those gaps.
However, more than half of the sequences of the Y chromosome, which is the smallest and most complicated of the 46 human chromosomes, remained unknown. Now, the same group of researchers completed the missing information, publishing this Wednesday a complete sequence of the Y chromosome in the academic journal Nature.
“Just a few years ago, half of the human Y chromosome was missing.” Monika Cechova, who is a main co-author of the paper and a postdoctoral fellow in Biomolecular Engineering at the University of California, in Santa Cruz, states in a statement.
“At the time, we didn't even know if it could be sequenced, it was so puzzling,” Cechova explained. “It is really a breakthrough in what is possible.”
Comments:
As you can see in both of the above translations using two different CAT tolls (Smartcat and DeepL), they are quite similar. I have put it in blue to see the differences between them, but actually, they are synonyms. However, I have found some mistakes or things that both CAT tools don't take into consideration, such as putting words in italics, correcting some grammar rules, and giving the article more coherence in the meaning. Therefore, I rewrote my own translation using different translation techniques like addition, commission, borrowing, calque, and transposition as you can appreciate the lines above.