Structural analysis of vaccine construct

Secondary Structure

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Secondary structure prediction of the final vaccine sequence using (a) CFSSP, (b) and (c) PSIPRED. (d) Graph of normalized B-factor predicted by I-TASSER.

Tertiary Structure

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Modeling, refinement and validation of Tertiary structure. (a) Multi-epitope vaccine chimeric protein 3D model generated using homology modelling. (b) Refined model using ModRefiner. (c) GalaxyRefine generated refined 3D structure. (d) Ramachandran plot of vaccine construct V1. (e) Prosa-Web giving a Z- score of -2.9.