Identification of PVC

Potential vaccine Candidates

A potential vaccine candidate may refer as the proteins possessing the idealistic characteristics like non toxic, non allergenic, non homologous to humans. In this study, we have shortlisted sets of PVC determined from diverse approach including Vax-Elan, Shuffling of Vax-Elan & ORF based approach.

For Strategies, Refer to Methodology section. Here, we are showing the standard Vax-Elan pipeline(Strategy 1) to find the potential vaccine candidate and their subsequent analysis for vaccine construction.

These 100 proteins were subsequently evaluated using their antigenic propensity score. The top 8 proteins with the highest antigenic score were selected from unique families.