Methodology
Features and Thresholds
Features and Thresholds
The features used in Vax-ELAN include cellular localization, secretory/non-secretory protein, stability, cleavage sites, adhesion property, CTL epitope prediction, MHC class-I binding, transmembrane helix prediction, essentiality, virulence, molecular weight, non-homology with host proteins, etc.
Methodology - Features and Thresholds.xlsx
List of tools used for extraction of features along with their cut-off values and justification
Strategies Used to Shortlist Vaccine Targets
Strategies Used to Shortlist Vaccine Targets
Vax-ELAN has provision to scan protein sequences (or proteomes) using multiple strategies
Schematic representation of different strategies with relevant characteristics (features) used in Vax-Elan