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Vax-ELAN
INTRODUCTION
Methodology
Strategy 1
Strategy 2
Strategy 3
Strategy 4
APPLICATION: CHAGAS DISEASE
Methodology
Retrieval of Data
Strategies for Potential Vaccine Candidate Identification
Strategy 1
Strategy 2
Strategy 3
Strategy 4
Strategy 5
Comparative analysis of Strategies
Identification of Epitopes
Identification of B cell epitopes
Identification of CTL epitopes
Identification of HTL epitopes
Epitope identification using different tools
Vaccine construction using consensus approaches(Tools)
Comparison of Conserved Domains
Comparison using different servers.
Randomisation Experiment
Structural Analysis
Limitations of other pipelines
Evaluation of genetic diversity
Variability Sequence Analysis of T.Cruzi epitope
Peptide receptor docking
Results
Identification of PVC
Epitope identification using different tools
Randomisation experiment
Comparison of Conserved Domains
Clustering of epitopes
Vaccine Construction
Structural analysis of vaccine construct
Discontinuous B-cell epitopes identification and analysis
Docking Studies
Codon optimisation Study
Immune Response Simulation Result
Top 10 potential vaccine candidates of pathogens
Top 10 potential vaccine candidate of T. cruzi (Species/Strains)
Evaluation of genetic diversity
Variability Sequence Analysis of T.Cruzi epitope
Peptide receptor docking
Section 1
Section 2
References
Data Download
Evidence for Protein Candidates
Lucas Work
Scripts
About Us
Supplementary Datas
Datasets
Web Documentation
Result Interpretation
Parameter Descriptions
Revision supplementary files
Supplementary data for Y-strain
Supplementary data for comments
Vax-ELAN
References
New Referencing Chagas Disease (After Hotez edits).docx
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