Epitope identification using
different Tools
A comprehensive analysis to determine the antigenic, immunogenic, non-toxic, and non-allergenic epitopes was conducted (see methodology for details). These properties were studied extensively to identify epitopes through several tools. Apart from using a robust approach, certain additional tools were also applied to find out the common epitopes.
A comprehensive analysis to determine the antigenic, immunogenic, non-toxic, and non-allergenic epitopes was conducted (see methodology for details). These properties were studied extensively to identify epitopes through several tools. Apart from using a robust approach, certain additional tools were also applied to find out the common epitopes.
Comparison of all B and T-cell epitope identified by various tools.
Comparison of all B and T-cell epitope identified by various tools.
Comprehensive analysis includes employing several tools:
CTL epitope prediction using NetCTL, NetMHC, EpiJen & Propred-1.
HTL epitope prediction using MHC2Pred, Propred & IEDB MHC-2
B-Cell epitope prediction using ABCPred, Bepipred & BCEPRED.
Following is the gdrive link uploaded having raw data compilation of all the 8 proteins:
We have also attempted to find the common overlapping epitopes (sequences) using python scripts, . The script and subsequently their analysed files are provided in the following link:
24 Epitopes Analysis
**Denotes the motif was found in overlapped data. Ex: ABC in ABCDEF
^^Denotes partial overlap of sequence residues were found to be present in data. EX: ABC in FGHABI