created by Geraldine_VdAuwera
on 2015-10-15
Geraldine Van der Auwera presented this talk as part of the Broad Institute’s Medical and Population Genetics (MPG) Primers series.
This talk provides a high-level overview of the workflow for performing variant discovery on high-throughput sequencing data, as described in the GATK Best Practices and implemented in the Broad’s production pipelines.
The following points emphasized in this presentation are:
- Informational content of data file formats and flow of information throughout the pipeline
- Concepts involved in the data transformations (processing steps and analysis methods)
- Motivation and key mechanics of the GVCF workflow for scalable joint variant discovery
- Relation of the GATK Best Practices to the Broad’s production pipeline implementation
The presentation slide deck is available at this [link](https://drive.google.com/open?id=0BwTg3aXzGxEDYzJpbWdMbEloN0U).