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Supranational TB Reference Laboratory in Tokyo, Japan
Address:
Department of Mycobacterium Reference and Research,
Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association,
3-1-24 Matsuyama, Kiyose,
TOKYO 204-8533, Japan
Contacts:
Satoshi Mitarai (mitarai@jata.or.jp)
Akiko Takaki (takaki@jata.or.jp)
Website:
Description
Our laboratory serves as actual national tuberculosis reference laboratory in Japan, and as supra-national reference laboratory in the Western Pacific.
Structure and organization
Bacteriology division is a part of the Research Institute of Tuberculosis.
Services provided by the SRL
All mycobacterial examinations, including smear, culture, species identification, drug susceptibility testing, molecular examinations and consultations to other laboratories.
Current links and partnerships outside of SRLN
The Research Institute of Tuberculosis has official link with Nagasaki University and accept post-graduate students.
Additional information:
Research activities
New diagnostics development, drug resistance survey, NTM-epidemiology, Molecular epidemiology
Publications
1. Yi L, Sasaki Y, Nagai H, Ishikawa S, Takamori M, Sakashita K, Saito T, Fukushima K, Igarashi Y, Aono A, Chikamatsu K, Yamada H, Takaki A, Mori T, and Mitarai S. Evaluation of QuantiFERON-TB Gold Plus for Detection of Mycobacterium tuberculosis infection in Japan. Sci Rep 2016; 29; 6: 30617.
2. Namkoong H, Kurashima A, Morimoto K, Hoshino Y, Hasegawa N, Ato M, Mitarai S. Nationwide survey on the epidemiology of pulmonary nontuberculous mycobacterial disease in Japan. Emerg Infect Dis 2016; 22(6): 1116–1117.
3. Kuroda M, Iwamoto T, Murase Y, Mitarai S, Kato S. Total Genotyping Solution for Mycobacterium tuberculosis using short-read whole-genome sequencing. Pros One 2015; 10(11):E0142951
4. Yoshimatsu S, Kato MT, Aono A, Chikamatsu K, Yamada Y, and Mitarai S. Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads. Int J Mycobacteriol 2015; 25(6): 245-249.
5. Kokuto H, Sasaki Y, Yoshimatsu S, Mizuno K, Yi L, Mitarai S. Detection of Mycobacterium tuberculosis (MTB) in fecal specimens from adults diagnosed with pulmonary tuberculosis using the Xpert MTB/Rifampicin test. Open Forum Infect Dis. 2015; 22; 2(2): ofv074.
6. Tuberculosis Research Committee (RYOKEN). Nationwide survey of anti-tuberculosis drug resistance in Japan. Int J Tuber Lung Dis 2015; 19(2): 157-162.
7. Aono A, Chikamatsu K, Yamada H, Kato K, Mitarai S. The association between pncA gene mutations, pyrazinamidase activity and pyrazinamide-susceptibility testing in Mycobacterium tuberculosis. Antimicrobiol Agent Chemother 2014 Aug; 58(8): 4928-4930.
8. Ueyama M, Chikamatsu K, Aono A, Murase Y, Kuse N, Morimoto K, Okumura M, Yoshiyama T, Ogata H, Yoshimori K, Kudoh S, Azuma A, Gemma A, Mitarai S. Sub-speciation of Mycobacterium tuberculosis complex from tuberculosis patients in Japan. Tuberculosis (Edinb). 2014 Jan; 94(1): 15-9.
9. Mitarai S, Karinaga R, Yamada H, Mizuno K, Chikamatsu K, Aono A, Sugamoto T, Hatano T. TRICORE, A novel bead–based specimen concentration method for the culturing of Mycobacterium tuberculosis. J Microbiol Method 2012; 90: 152-155.
10. Mitarai S, Kato S, Ogata H, Aono A, Chikamatsu K, Mizuno K, Toyota E, Sejimo A, Suzuki K, Yoshida S, Saito T, Moriya A, Fujita A, Sato S, Matsumoto T, Ano H, Suetake T, Kondo Y, Kirikae T, Mori T. Comprehensive multicenter evaluation of a new line probe assay kit for identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis. J Clin Microbiol. 2012; 50: 884-890.
Trainings
Laboratory Training course through September to December (9 weeks) supported by JICA
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