In a recent paper from our projects, we observed that changes in saddle height as large as 3 cm have a very small impact in knee loads. We used 3D full body musculoskeletal modeling and compared temporal influences of changes in saddle height through the crank cycle, which highlighted that, when knee forces are large, there is no meaningful implication in knee loads. This finding provides further evidence that development of knee pain and injuries may largely associated with cadence to gear ratio, training loads and history of other illnesses, as demonstrated in prior studies. It is critical to note though that, avoiding an excessively low saddle height is important because overloading the knees can be associated with excessively low saddle heights. This means that, small changes in body position on the bike are not that critical, but a reasonably effective bike fitting should minimise major errors in body position whilst cycling.