In a recent study from our lab, we assessed whether lower limb preference was related to cartilage thickness and if greater muscle strength was also associated with thicker cartilage. Key findings were that there was no relationship between lower limb preference and cartilage thickness but participants with a prior injury in the lower limbs had greater bilateral differences in cartilage thickness. This finding is important because it seems to indicate that those with a history of injury are more prone to present greater asymmetries in cartilage thickness and potentially increased risk of osteoarthritis. In addition, participants with greater muscle strength had thicker cartilage in their knees, which suggests a potential protective mechanism from muscle strength. This last finding stresses the important of engaging in resisted training at a minimum of two sessions per week, as currently recommended by the WHO and other health bodies.