ISO - the sensitivity of the film or sensor of of your camera to the
light levels falling onto it from the lens.
Low ISO - iso of 100 in bright sunny scenes or scenes where you
want to decrease you shutter speed in order to blur
motion.
High ISO - iso of 400 to 1600 in low light level scenes where you
want to increase the shutter speed of a handheld shot
to avoid camera shake i.e. churches, museums, late
evening shots when you do not have a tripod at hand
or if you are just trying to introduce some noise into
your photograph for effect (black and white portrait).
Note - As you increase the iso from 100 to 400 you are reducing
your camera sensor's dynamic range, the sensor's ability
to capture the brightest and darkest parts of a high
contrast scene such as a sunrise or sunset scene. as
opposed to an overcast day where these differences are
much less, a narrow dynamic range.
Note - As you increase your iso you are reducing your camera’s
Sensor ability to record all the colours present in a scene.
A setting of iso 100 will record more color range then an
ISO setting of 800.