Maria Francesca Allega

I graduated in Molecular and Cellular Biology at the University of Bologna in March 2017. During the first year of Master Degree, I got closer to the fascinating and complex world of Bioinformatics and thanks to Elena Papaleo and an Erasmus Traineeship, I have the opportunity to see it with my own eyes. I carried out my Master thesis at the interface between Elena's group and Giuseppe Filomeni's group (Unit of Cell Stress and Survival, DCRC). The final purpose of my project is to obtain a molecular model of redox modifications of cysteines in an oncogenic mitochondrial chaperone and to validate it experimentally in vitro and in vivo.

I am currently working at CBL as Research Assistant where I am continuing my research in computational and experimental biology of chaperones and kinases, as well as I am now approaching to the world of analysis and interpretation of sequencing data from NCI's Genomic Data Commons and other similar initiatives with focus on brain tumors.

Publications at CBL:

Salamanca Viloria J., Allega M.F., Lambrughi M., Papaleo E*. An optimal distance cutoff for contact-based Protein Structure Networks using side-chain centers of mass. Nature Scientific Reports 2017 (doi: 10.1038/s41598-017-01498-6SREP-17-01869, in press)