In the first sentence, it implies that "tourists" is a popular destination for cruise ships. "Tourists" are people and not a place, so this sentence is incorrect.
In the second sentence, it implies that "Key West" is a popular destination for cruise ships. "Key West" is a place so this sentence is correct.
The house was robbed by the thief, and the thief was arrested by the police chief.
We were on vacation in Florida and saw several peacocks.
Driving up in his police car, the officer found the lost child.