Antibiotics- Using A Combination
Antibiotics- Using A Combination
We've known for years that the standard course of antibiotics (IDSA/CDC recommended) were not able to kill all of the spirochetal organisms in someone who had Lyme disease. Due to this situation, many people became chronically ill, disabled and some died.
We also know that people may be infected with multiple parasites, viruses and bacteria after being bitten by ticks. The "deer tick" alone (backlegged tick- Ixodes scapularis) has been shown to harbor 91 different pathogens.
Lab studies indicate a four drug combination of...
dapsone+minocycline+cefuroxime+azithromycin and dapsone+minocycline+cefuroxime+rifampin
Showed best activity against stationary phase B. burgdorferi in these sulfa drug combinations.
With this in mind, experienced Lyme treating health care professionals have successfully used, as needed, a combination of antimicrobials to treat sick patients.
In fact, in the guidelines by Dr. Joseph J. Burrascano, Jr. there are different options for patients who do not get well or stay well after a course of treatment.
Some of the antibiotics that tested successfully in the lab at killing all forms of the Borrelia spirochetes were combined and used by a long-time treating doctor (Dr. Richard Horowitz) in clinical studies of Lyme patients. Those published studies can be found below.
NOTE- Additional studies need to be done before the kinks found in any human treatment protocols can be addressed.
Horowitz RI, Freeman PR.
Int J Gen Med. 2019 Feb 18;12:101-119. doi: 10.2147/IJGM.S193608. eCollection 2019.
~~
Horowitz RI, Freeman PR.
Healthcare (Basel). 2018 Nov 5;6(4). pii: E129. doi: 10.3390/healthcare6040129.