Cannabis has THC that causes large dopamine surges, creating intense pleasure that the brain learns to crave, shifting focus from healthy rewards leading The brain to reduces its natural cannabinoid production and sensitivity, leading to tolerance (needing more for the same high) and physical dependence while Some people are genetically more susceptible to addiction, with studies showing genetics can account for 40-60% of vulnerability to substance use disorders. While other people use cannabis to cope with stress, anxiety, depression, loneliness, Trauma, and difficult upbringings increase vulnerability, it creates a reliance, worsening underlying issues over time, becoming a way to escape reality or manage emotions, even when enjoyment fades, leading to a cycle of use to deal with problems created by use. The environment can also play an important role. Widespread availability increases the risk of initiation and problematic use, especially during adolescence, as well as when people use with friends or in social settings, which normalizes the behavior.