The Boeing 777-300ER fleet consists of 20 aircraft and is American's Flagship plane. American was the first US carrier to operate the 77W. The entire 77W fleet is powered by General Electric’s GE90-115B1 engines and are all ETOPS certified.

The 77W has 8 Flagship First Class Suites in a 1-2-1 layout. 52 Safran Cirrus (formerly Zodiac Cirrus) Flagship Business Class Suites in a 1-2-1 layout. 28 Premium Economy Class seats in a 2-4-2 layout. And Main Cabin and Main Cabin Extra is in a 3-4-3 layout. This fleet type has Panasonic high speed satellite Wi-Fi and Live TV. The Boeing 777-300ER flies mostly to LHR, GRU, EZE, DEL, HNL and HKG from hubs at LAX, DFW, MIA, and JFK.