TRANSCEND

Who do I contact about this study? Please contact Eric Williamson at will0188@umn.edu for more information about how to get involved with this study. 

Who can participate? You may be eligible for this study if you: 

• Are 22-70 years old

• Have been diagnosed with depression

• Are open to receiving an investigational surgical option for your depression

• Have tried at least 4 different treatments and not found them helpful 

What will I do if I participate? This study takes place primarily at the St. Louis Park Interventional Psychiatry Clinic. If you decide to take part in this research study, the general procedures include a screening period, which includes 3 baseline visits, surgical implantation of the Abbott’s Infinity™ DBS system, and randomization. There then are 2 phases in the research. For Phase A, you will have 14 visits with the study team (with a small number being telephone visits) during the first 12 months after the DBS System is implanted. During Phase A, half of the participants are randomized to have the device turned on and half are randomized to the delayed stimulation group, in which the device will not be turned until Phase B. After the first 12 months, you will begin Phase B and be asked to return to the clinic every 6 months for 2 years. These visits may include questionnaires, imaging and exams. During Phase B, all participants will have the device turned on. 

Will I be compensated? The device, surgical procedure, and study follow-up care will be provided at no cost to you. Travel reimbursement may be provided for follow-up visits. 

For more information, visit our website TNE Lab or scan the QR code below: