From An Introduction to Statistical Learning with Applications in R (Hastie Tibshirani) - Section 2.2.2 "The Bias-Variance Trade-Off"
E(y0 - f-hat(x0))2 = Var(f-hat(x0)) + [Bias(f-hat(x0))]2 + Var(ɛ)
Quoted: It is possible to show that the expected test MSE, for a given value x0, can always be decomposed into the sum of three fundamental quantities;
Variance of f-hat(x0)
Squared bias of f-hat(x0)
Variance of the error terms ɛ
Dr. Hyndman provides a break-down of the math behind the bias-variance decomposition.
There are some situations where allowing a little bias can provide a useful reduction in variance.