Masters Applied Projects

Project 12

Surface Plasmon Resonance Imaging Device Flow Cell


Student:
Zachary Fisher

Mentors:
Dr. Mehdi Nikkhah, PhD – Arizona State University, SBHSE
Dr. Vincent Pizziconi, PhD– Arizona State University, SBHSE
Dr. Shaopeng Wang, PhD– Arizona State University, SBHSE

YouTube Link:
View the video link below before joining the zoom meeting

Zoom Link:
https://asu.zoom.us/j/87137736558


Abstract
Surface plasmon resonance (SPR) scattering is a technique used for molecular imaging. This technique is performed by specialized machines. The purpose of this endeavor is to create a flow cell for a specific SPR device. The flow cell of an SPR device is a part through which the substance being imaged flows. It is in the flow cell that the substance is imaged. The most notable requirement of the device in question is that light source is mounted below the flow cell and the light refracted from the substance is imaged from above the sample. As such, a flow cell as been created around these requirements, including a vertical gap in the middle of the flow cell to allow for imaging and a design that allows for equal pressure distribution across the flow cell. We will test the device for leaking with a water flow test and ensure all of the parts fit together and can be securely mounted on the SPR device. The results of these studies show that there is no leaking and that the parts fit for their intended purpose.