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Articles published in 2024
Articles published in 2024
Biotechnology | Food Science | Functional Metabolite
Bioactive exopolysaccharide from Limosilactobacillus fermentum LAB-1: antioxidant, anti-inflammatory, antibacterial and antibiofilm properties
Bioactive exopolysaccharide from Limosilactobacillus fermentum LAB-1: antioxidant, anti-inflammatory, antibacterial and antibiofilm properties
Nowshin Tarannum, Ferdausi Ali, Md Sajib Khan, Ohoud S Alhumaidan, ANMS Zawad, Tanim Jabid Hossain*
Bioactive Carbohydrates and Dietary Fibre, 2024
| Author-note | This study highlights the diverse and beneficial roles of the exopolysaccharide (EPS) produced by our isolate, LAB-1. Building on previous genomic analyses that predicted LAB-1's EPS production potential, we now provide experimental evidence to support these findings. The extracted EPS demonstrated an impressive range of bioactive properties, including potent antioxidant activity, broad-spectrum antimicrobial effects against Gram-positive and Gram-negative bacterial pathogens, inhibition of biofilm formation in key pathogens such as S. aureus and E. coli, notable anti-inflammatory activity, and emulsification capabilities. These results advance our understanding of the functional versatility of EPS and underscore its potential for practical applications. As a sustainable and eco-friendly alternative, LAB-1 EPS addresses the growing global demand for innovative, environmentally conscious products and processes.
Natural Pigment | Antiviral | In-Silico
Prodigiosin Demonstrates Promising Antiviral Activity Against Dengue Virus and Zika Virus in In-silico Study
Prodigiosin Demonstrates Promising Antiviral Activity Against Dengue Virus and Zika Virus in In-silico Study
Tanjilur Rahman, Mohammed Sajjad Hossain Bappi, Tanim Jabid Hossain*
Analytical Science Advances, 2024
| Author-note | We provided a detailed computational analysis of prodigiosin, a natural tripyrrole compound, as a promising antiviral agent against Dengue (DENV) and Zika (ZIKV) viruses. With the rising global burden of DENV and ZIKV infections and the absence of effective antiviral therapies, the identification of novel treatment candidates is increasingly critical. Using state-of-the-art computational approaches, including molecular docking and molecular dynamics simulations, we investigated the interactions between prodigiosin and key viral proteins, NS3 helicase and NS5 methyltransferase. Our results demonstrate that prodigiosin exhibits strong binding affinities to these target proteins, suggesting its potential to inhibit viral replication. Particularly, prodigiosin formed multiple stable interactions, including hydrogen bonds, with active site residues of NS5 methyltransferase, further enhancing its inhibitory effect. Moreover, the compound’s favorable drug-likeness and ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties underscore its potential as a safe and effective antiviral candidate. These findings position prodigiosin as a promising lead compound for further development in the fight against DENV and ZIKV.
Plant-microbe interaction | Sustainable Agriculture
Multifaceted plant growth promoting traits and abiotic stress resistance abilities exhibited by chrysanthemum rhizobacteria
Multifaceted plant growth promoting traits and abiotic stress resistance abilities exhibited by chrysanthemum rhizobacteria
Mohammad Nazmul Ahmed Chowdhury, Tanim Jabid Hossain*, Subrina Akter Zedny, Mohammed Sajjad Hossain Bappi, Minhajur Rahman, Md Hossen, Iqbal Hossain Nafiz, Raihanul Islam
Current Applied Science and Technology, 2024
| Author-note | Our study focuses on the isolation and characterization of 34 bacterial strains from the root-associated soil of Chrysanthemum. Among these, seven strains exhibited multiple plant growth-promoting traits, including auxin production, phosphate solubilization, nitrogen fixation, and ammonia production. These strains were identified as belonging to the genera Pantoea, Staphylococcus, Acinetobacter, Bacillus, and Serratia. The selected strains also demonstrated resilience to abiotic stresses, such as osmotic and salt stress, as well as temperature variations, underscoring their potential applicability in diverse environmental conditions. Our findings suggest that these rhizobacteria could significantly promote plant growth and sustainability in agroecosystems. Additionally, their ability to produce hydrolytic enzymes enhances their utility as biofertilizers. This study provides valuable insights into the development of eco-friendly strategies to improve crop productivity and sustainability in global agriculture.
Probiotics | Lactic Acid Bacteria | Fermented Food
Assessment of the In-Vitro Probiotic Efficacy and Safety of Pediococcus pentosaceus L1 and Streptococcus thermophilus L3 Isolated from Laban, a Popular Fermented Milk Product
Assessment of the In-Vitro Probiotic Efficacy and Safety of Pediococcus pentosaceus L1 and Streptococcus thermophilus L3 Isolated from Laban, a Popular Fermented Milk Product
Shanta Paul, Tanim Jabid Hossain*, Ferdausi Ali, Md Elias Hossain, Tasneem Chowdhury, Ibrahim Khalil Faisal, Jannatul Ferdouse*
Archives of Microbiology, 2024
| Author-note | In this study, we have evaluated the probiotic potential and safety aspects of lactic acid bacteria (LAB) isolated from Laban, a traditionally consumed dairy beverage. The LAB strains exhibited antagonistic effects against bacterial and fungal pathogens, antioxidant capacity, and tolerance to low pH, bile salts, and phenols. Additionally, these strains have demonstrated adhesion ability to ethyl acetate, chloroform, and xylene, along with autoaggregation and coaggregation properties. Moreover, the isolates displayed promising technological attributes, such as milk coagulation and exopolysaccharide production, suggesting their potential to enhance the quality of dairy products. Our research underscores the potential of LAB from Laban in imparting health benefits to consumers. The natural presence of these beneficial microbes in fermented dairy products, such as Laban, offers an added advantage for individuals aiming to enhance their health through diet.
Antimicrobial Assay | Antimicrobial Susceptibility Test
Methods for screening and evaluation of antimicrobial activity: a review of protocols, advantages and limitations
Methods for screening and evaluation of antimicrobial activity: a review of protocols, advantages and limitations
Tanim Jabid Hossain*
European Journal of Microbiology and Immunology, 2024
| Author-note | The global concern surrounding antimicrobial resistance remains pressing, necessitating the discovery of novel and effective antimicrobial agents. This review delves into a range of established and emerging techniques, including disk diffusion assay, well diffusion, spot assay, cross-streaking method, poisoned food method, agar dilution, broth macrodilution and microdilution, resazurin assay, co-culture technique, time-kill kinetics, flow cytometry, TLC bioautography, bioluminescence assay and impedance measurement. Each method's principle, advantages, limitations, and significance in antimicrobial screening and evaluation have been discussed. The review aims to provide researchers, professionals, and practitioners in medicine, infectious disease, clinical microbiology, biotechnology, and pharmaceutical fields with an understanding of these antimicrobial evaluation techniques. By elucidating the strengths and limitations of each method, this paper seeks to empower researchers in making informed decisions on selecting appropriate assays for the efficient identification of potential antimicrobial agents.
Fermented Beverages | Probiotics | Lactic Acid Bacteria
Fermented and dairy beverages of Bangladesh: a rich source of probiotic lactic acid bacteria
Fermented and dairy beverages of Bangladesh: a rich source of probiotic lactic acid bacteria
Tanim Jabid Hossain*, Md. Sajib Khan, Jannatul Ferdouse
Food Science and Applied Biotechnology, 2024
| Author-note | We explored the rich landscape of traditional fermented and dairy beverages in Bangladesh, emphasizing their role as valuable reservoirs of probiotic lactic acid bacteria. Highlighting their cultural significance, the paper uncovers the microbial diversity within these beverages, showcasing their antimicrobial properties, antioxidant effects, cholesterol-lowering abilities, and exopolysaccharide production. By connecting the traditional practices with modern genomic insights, this work underlines the global relevance of probiotic-rich beverages in promoting health and nutrition.
Biosurfactant | Oil-emulsification
Isolation of Biosurfactant Producing Bacteria from Oil-Spilled Soil and Characterization of Their Secreted Biosurfactants in Pathogen-Inhibition and Oil-Emulsification
Isolation of Biosurfactant Producing Bacteria from Oil-Spilled Soil and Characterization of Their Secreted Biosurfactants in Pathogen-Inhibition and Oil-Emulsification
Mohammad Zobaer, Ferdausi Ali, Md Nural Anwar*, Mohammed Sajjad Hossain Bappi, Takia Binte Bakar, Tanim Jabid Hossain, Md. Sajib Khan, ANM Shahriar Zawad
International Journal of Pharmaceutical Sciences and Research, 2024
| Author-note | In this research, we’ve isolated and selected two promising bacterial strains based on their biosurfactant production, and performed an intensive characterization of the strains, and their secreted surfactants. The partially purified biosurfactants had relatively high activity forming stable emulsions with different hydrocarbons and also showed good antimicrobial activity. Moreover, the biosurfactants exhibited high levels of pH, salinity and thermal stability, and ability to degrade diesel oil which indicate their prospect for application in bioremediation and oil recovery under extreme conditions.
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