Dept of Biochemistry and Molecular Biology, University of Chittagong
Laboratory for Health, Omics and Pathway Exploration (HOPE Lab)
Seeking to elucidate the dynamic interactions among organisms, the environment, and metabolites, my research focuses on how microbial life influences human health and environmental sustainability. By investigating metabolic pathways, probiotic activities, pathogenic mechanisms, and their ecological impacts, I aim to uncover sustainable, evidence-based solutions to pressing health and environmental challenges. My work spans microorganisms, microinvertebrates, and their roles in processes such as biogeochemical carbon cycling and inter-organismal interactions. A core aspect of this research includes the development of One Health-oriented probiotics, functional foods and microbiome-driven systems, alongside food microbiology and evidence-based probiotic formulation strategies that support human, animal, and plant health through sustainable, biologically informed approaches.
During my academic journey, I completed a Ph.D. in the Glycometabolome Lab under the guidance of Dr. Tadashi Suzuki at RIKEN, Japan, as part of a joint doctoral program with Saitama University. This transformative experience ignited my fascination for microbial metabolic pathways, particularly protein glycosylation and the catabolism of glycoconjugates. My research focused on understanding N-linked glycans and their structural variations in Saccharomyces cerevisiae and exploring the degradation of C-linked glycoconjugates by prokaryotes, providing insights into microbial glycan processing pathways.
As an Associate Professor in the Department of Biochemistry and Molecular Biology, I am dedicated to integrating teaching with research. I teach microbiology, spectroscopy, natural products, and related disciplines at the undergraduate and postgraduate levels. Beyond academics, I foster collaborative, mentorship-driven learning environments, aiming to develop independent, critical-thinking researchers while continuously learning alongside them.
In my research, I employ biochemical, genetic, and omics-driven approaches to study organisms with beneficial and pathogenic roles. These include probiotics, plant growth-promoting microbes, zoonotic and phytopathogens, and extremophiles, with a focus on their bioactive metabolites, ecological functions, and interspecies interactions. A key area of my work involves multidrug-resistant pathogens and antimicrobial resistance (AMR), where I explore innovative interventions such as antimicrobial peptides, bacteriocins, exopolysaccharides, and other food-grade bioactive compounds to mitigate resistance and enhance global health outcomes.
Throughout my career, I have been involved in multidisciplinary research spanning metabolomics, genomics, and bioinformatics. My work seeks to bridge fundamental research with practical applications, such as bioprocess optimization, environmental sustainability, food safety and food preservation technologies. From investigating symbiotic ecosystem interactions to isolating industrially relevant enzymes, my research advances understanding of complex biological systems and their functional dynamics.
Driven by a strong commitment to advancing scientific knowledge, I continue to explore the biochemical and ecological roles of living systems while developing sustainable, health-oriented solutions. Equally important is my dedication to mentorship and capacity building, creating a research environment where students grow into independent scientists and impactful contributors, ensuring that our work advances both science and society.
PhD in Science & Engineering (Glycobiology)
RIKEN-Saitama University Graduate Program, Japan
MS in Biochemistry and Molecular Biology
University of Chittagong, Bangladesh
BSc in Biochemistry and Molecular Biology
University of Chittagong, Bangladesh
Associate Professor
Dept. of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh
2022 – Present
Assistant Professor
Dept. of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh
2017 – 2022
Lecturer
Dept. of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh
2014 – 2017
International Program Associate
Glycometabolome Team, RIKEN, Japan
2012 – 2015
Executive
Production Department, Square Toiletries Ltd
2011 – 2012
Executive
Quality Assurance Department, ACI Pharmaceuticals Ltd.
2010 – 2011
Title: Analysis of the catabolic pathways of glycoconjugates
Institute: RIKEN-Saitama University Joint Program, Japan
Major Topics:
Catabolism of protein-N-glycans in Sacchormyces cerevisae
Structure-analysis of free-N-glycans (FNGs)
Bacterial degradation of C-Mannosyl Tryptophan
Title: Chemical and microbiological quality assessment of raw and processed (pasteurized and UHT-treated) liquid market milks of Bangladesh
Institute: Dept. of Biochemistry and Molecular Biology, University of Chittagong
Major Topics:
Chemical analysis: nutritional composition, determination of acidity and adulteration
Microbial analysis: bacterial enumeration and biochemical characterization
Major Topics:
Biocatalysis, PGPR, Probiotics
Microbial Symbiosis, Ecology
Postgraduate students: 2
MS thesis students: 7
Undergrad students: 7
Research Field
Microbial Biochemistry, Genomics, Glycomics
Functional foods, Nutraceuticals, Microbial pathogenesis
Area of Interest
One-Health Probiotics
Food and Nutritional Microbiology
Sustainable applications in health and food
Ecology, Symbiosis
Phytopathogens, Zoonoses
Biocatalysis, Glycoconjugates
Genome sequence, Bioinformatics
Nafiz, I. H., Akter, J., Akhter, K., Khan, M. S., Hasan, S., Bappi, M. S. H., Rahman, T., Faisal, I. K., Chowdhury, M. N. A., Zedny, S. A., Ali, F., Uddin, M. K., & Hossain, T. J.*
Islam S, Hossain TJ*, Afrin S, Paul S, Bappi MS, Ali F, Ferdouse J *
Scientific Reports; 2026
T Rahman, Golam Mostofa, TJ Hossain*
T Rahman, MSH Bappi, TJ Hossain*
J Ferdouse*, S Paul, MM Chowdhury, F Ali, TJ Hossain*
Annals of Agri-Bio Research; 2025
T Rahman, MSH Bappi, TJ Hossain*
Analytical Science Advances; 2024
S Islam, TJ Hossain*, A Sanjida, S Paul, MSH Bappi, F Ali, J Ferdouse*
Preprint; 2024
N Tarannum, F Ali, MS Khan, OS Alhumaidan, ANMS Zawad, TJ Hossain*
Bioactive Carbohydrates and Dietary Fibre; 2024
S Paul, TJ Hossain*, F Ali, M Elias Hossain, T Chowdhury, IK Faisal, J Ferdouse*
Archives of Microbiology; 2024
TJ Hossain*, S Hossain, IH Nafiz, R Islam, MS Khan
MNA Chowdhury, TJ Hossain*, SA Zedny, MSH Bappi, M Rahman, IH Nafiz, R Islam
Current Applied Science and Tehcnology; 2024
M Zobaer, F Ali, MN Anwar, MSH Bappi, TB Bakar, TJ Hossain, MS Khan, ANMS Zawad
International Journal of Pharmaceutical Sciences and Research; 2024
TJ Hossain*
European Journal of Microbiology and Immunology; 2024
Phosphate solubilizing rhizobacteria of rice: Analysis of plant growth promoting activity and environmental stress tolerance
T Basharat, F Ali, T Das, TB Bakar, NT Mishi, J Ferdouse, MS Uddin, TJ Hossain*
Annals in Agribio Research; 2023
NT Mishi, TJ Hossain*, F Ali, T Das, K Dhar, IH Nafiz
LWT - Food Science and Technology; 2023
TJ Hossain*, IHN Nafiz, HA Mozumder, F Ali, N Rahman, MS Khan
Journal of Microbiology, Biotechnology and Food Sciences; 2023
J Ferdouse*, S Paul, T Chowdhury, F Ali, S Islam, TJ Hossain*
Applied Food Biotechnology; 2023
TJ Hossain*
Acta Scientiarum. Biological Sciences; 2023
TJ Hossain*, HA Mozumder, F Ali, K Akther
Current Research in Nutrition and Food Science; 2022
Functional Genomics of the Lactic Acid Bacterium Limosilactobacillus fermentum LAB-1: Metabolic, Probiotic and Biotechnological Perspectives
TJ Hossain*
Heliyon; 2022
TJ Hossain*, M Das, F Ali, SI Chowdhury, SA Zedny
AIMS Microbiology 7(4); 2021
F Ali*, S Das, TJ Hossain*, SI Chowdhury, SA Zedny, T Das, MNA Chowdhury
Royal Society Open Science 211003; 2021
MM Uddin, SA Lima, TJ Hossain, N Kar, Y Zahan, BA Olarewaju
Tropical Life Science Research 32(3); 2021
F Ali, TN Silvy, TJ Hossain*, MK Uddin, MS Uddin
International Journal of One Health 7 (2), 158-164; 2021
TJ Hossain*, SI Chowdhury, HA Mozumder, MNA Chowdhury, F Ali, N Rahman, S Dey
Frontiers in microbiology 11, 2097; 2020
TJ Hossain, S Manabe, Y Ito, T Iida, S Kosono, K Ueda, A Hosomi, D Inoue, T Suzuki
Glycoconjugate journal 35 (2), 165-176; 2018
TJ Hossain, Y Harada, H Hirayama, H Tomotake, A Seko, T Suzuki
PloS one 11 (3), e0151891; 2016
Lack of the Evidence for the Enzymatic Catabolism of Man1GlcNAc2 in Saccharomyces cerevisiae
TJ Hossain, H Hirayama, Y Harada, T Suzuki
Bioscience, biotechnology, and biochemistry 80 (1), 152-157; 2016
G Tzelepis, A Hosomi, TJ Hossain, H Hirayama, M Dubey, DF Jensen, T Suzuki, M Karlsson
Biochemical and biophysical research communications 449 (2), 256-261; 2014
TJ Hossain*, MK Alam, D Sikdar
Continental J. Food Science and Technology 5 (2), 6-17; 2011
M Zobaer, F Ali, A Hossain, TJ Hossain
Biochimica et Biophysica Acta
Frontiers in Bioengineering and Biotechnology
Current Microbiology
Applied Food Biotechnology
Jordan Journal of Biological Sciences
Biodiversitas Journal of Biological Diversity
etc.