Dept of Biochemistry and Molecular Biology, University of Chittagong
Laboratory for Health, Omics and Pathway Exploration (HOPE Lab)
Driven by a curiosity to decode the dynamic interactions among organisms, systems, and metabolites, my research focuses on how biological entities influence human health and environmental sustainability. By investigating metabolic pathways, probiotic activities, pathogenic mechanisms, and their broader ecological impacts, I aim to uncover sustainable solutions to pressing health and environmental challenges. My work spans microorganisms, microinvertebrates, and their roles in processes such as biogeochemical carbon cycling and inter-organismal interactions.
During my academic journey, I pursued a Ph.D. in the Glycometabolome Lab under the guidance of Dr. Tadashi Suzuki at RIKEN, Japan, as part of a joint doctoral program with Saitama University. This transformative experience ignited my fascination with microbial metabolic pathways, particularly protein glycosylation and the catabolism of glycoconjugates. My research focused on understanding N-linked glycans and their structural variations in Saccharomyces cerevisiae and exploring the degradation of C-linked glycoconjugates by prokaryotes, offering insights into microbial glycan processing pathways.
As an Associate Professor in the Department of Biochemistry and Molecular Biology, I am dedicated to both teaching and research. I teach courses in microbiology, spectroscopy, endocrinology, and other related subjects at the undergraduate and postgraduate levels. Beyond academics, I am committed to fostering a culture of collaboration, mentorship, and continuous learning, striving to empower aspiring researchers while embracing opportunities to learn from others.
In my research, I employ biochemical, genetic, and omics-based approaches to analyze organisms with beneficial and harmful impacts. These include probiotics, plant growth-promoting agents, zoonotic and phytopathogens, and extremophiles, focusing on their bioactive metabolites, ecological roles, and interactions with other life forms. A significant aspect of my work also involves studying multidrug-resistant pathogens and antimicrobial resistance genes, exploring innovative solutions such as antimicrobial peptides and bacteriocins to combat resistance and promote global health.
Throughout my career, I have been involved in multidisciplinary projects spanning metabolomics, genomics, and bioinformatics. My work seeks to bridge fundamental research with practical applications, such as bioprocess optimization, environmental sustainability, and food safety. From studying symbiotic relationships in ecosystems to isolating industrially significant enzymes, my research aims to contribute to the broader understanding of how biological systems interact and function.
Driven by a strong desire to advance knowledge, I am committed to exploring the biochemical and ecological roles of organisms while promoting strategies for health and environmental sustainability. Through research, mentorship, and collaboration, I aim to explore new frontiers in science, contributing to meaningful advancements that benefit both humanity and the planet.
PhD in Life Science
RIKEN-Saitama University Joint Program, Japan
MS in Biochemistry and Molecular Biology
University of Chittagong, Bangladesh
BSc in Biochemistry and Molecular Biology
University of Chittagong, Bangladesh
Associate Professor
Dept. of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh
2022 – Present
Assistant Professor
Dept. of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh
2017 – 2022
Lecturer
Dept. of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh
2014 – 2017
International Program Associate
Glycometabolome Team, RIKEN, Japan
2012 – 2015
Executive
Production Department, Square Toiletries Ltd
2011 – 2012
Executive
Quality Assurance Department, ACI Pharmaceuticals Ltd.
2010 – 2011
Title: Analysis of the catabolic pathways of glycoconjugates
Institute: RIKEN-Saitama University Joint Program, Japan
Major Topics:
Catabolism of protein-N-glycans in Sacchormyces cerevisae
Structure-analysis of free-N-glycans (FNGs)
Bacterial degradation of C-Mannosyl Tryptophan
Title: Chemical and microbiological quality assessment of raw and processed (pasteurized and UHT-treated) liquid market milks of Bangladesh
Institute: Dept. of Biochemistry and Molecular Biology, University of Chittagong
Major Topics:
Chemical analysis: nutritional composition, determination of acidity and adulteration
Microbial analysis: bacterial enumeration and biochemical characterization
Major Topics:
Biocatalysis, PGPR, Probiotics
Microbial Symbiosis, Ecology
Postgraduate students: 2
MS thesis students: 7
Undergrad students: 7
Research Field
Microbial Biochemistry, Ecophysiology
Biogeochemistry, Genomics, Pathogenesis
Area of Interest
Probiotics, Nutraceuticals
Ecology, Symbiosis
Phytopathogens, Zoonoses
Biocatalysis, Glycoconjugates
Genome sequence, Bioinformatics
J Ferdouse*, S Paul, MM Chowdhury, F Ali, TJ Hossain*
Annals of Agri-Bio Research; 2025
T Rahman, MSH Bappi, TJ Hossain*
Analytical Science Advances; 2024
S Islam, TJ Hossain*, A Sanjida, S Paul, MSH Bappi, F Ali, J Ferdouse*
Preprint; 2024
N Tarannum, F Ali, MS Khan, OS Alhumaidan, ANMS Zawad, TJ Hossain*
Bioactive Carbohydrates and Dietary Fibre; 2024
S Paul, TJ Hossain*, F Ali, M Elias Hossain, T Chowdhury, IK Faisal, J Ferdouse*
Archives of Microbiology; 2024
TJ Hossain*, S Hossain, IH Nafiz, R Islam, MS Khan
MNA Chowdhury, TJ Hossain*, SA Zedny, MSH Bappi, M Rahman, IH Nafiz, R Islam
Current Applied Science and Tehcnology; 2024
M Zobaer, F Ali, MN Anwar, MSH Bappi, TB Bakar, TJ Hossain, MS Khan, ANMS Zawad
International Journal of Pharmaceutical Sciences and Research; 2024
TJ Hossain*
European Journal of Microbiology and Immunology; 2024
Phosphate solubilizing rhizobacteria of rice: Analysis of plant growth promoting activity and environmental stress tolerance
T Basharat, F Ali, T Das, TB Bakar, NT Mishi, J Ferdouse, MS Uddin, TJ Hossain*
Annals in Agribio Research; 2023
NT Mishi, TJ Hossain*, F Ali, T Das, K Dhar, IH Nafiz
LWT - Food Science and Technology; 2023
TJ Hossain*, IHN Nafiz, HA Mozumder, F Ali, N Rahman, MS Khan
Journal of Microbiology, Biotechnology and Food Sciences; 2023
J Ferdouse*, S Paul, T Chowdhury, F Ali, S Islam, TJ Hossain*
Applied Food Biotechnology; 2023
TJ Hossain*
Acta Scientiarum. Biological Sciences; 2023
TJ Hossain*, HA Mozumder, F Ali, K Akther
Current Research in Nutrition and Food Science; 2022
Functional Genomics of the Lactic Acid Bacterium Limosilactobacillus fermentum LAB-1: Metabolic, Probiotic and Biotechnological Perspectives
TJ Hossain*
Heliyon; 2022
TJ Hossain*, M Das, F Ali, SI Chowdhury, SA Zedny
AIMS Microbiology 7(4); 2021
F Ali*, S Das, TJ Hossain*, SI Chowdhury, SA Zedny, T Das, MNA Chowdhury
Royal Society Open Science 211003; 2021
MM Uddin, SA Lima, TJ Hossain, N Kar, Y Zahan, BA Olarewaju
Tropical Life Science Research 32(3); 2021
F Ali, TN Silvy, TJ Hossain*, MK Uddin, MS Uddin
International Journal of One Health 7 (2), 158-164; 2021
TJ Hossain*, SI Chowdhury, HA Mozumder, MNA Chowdhury, F Ali, N Rahman, S Dey
Frontiers in microbiology 11, 2097; 2020
TJ Hossain, S Manabe, Y Ito, T Iida, S Kosono, K Ueda, A Hosomi, D Inoue, T Suzuki
Glycoconjugate journal 35 (2), 165-176; 2018
TJ Hossain, Y Harada, H Hirayama, H Tomotake, A Seko, T Suzuki
PloS one 11 (3), e0151891; 2016
Lack of the Evidence for the Enzymatic Catabolism of Man1GlcNAc2 in Saccharomyces cerevisiae
TJ Hossain, H Hirayama, Y Harada, T Suzuki
Bioscience, biotechnology, and biochemistry 80 (1), 152-157; 2016
G Tzelepis, A Hosomi, TJ Hossain, H Hirayama, M Dubey, DF Jensen, T Suzuki, M Karlsson
Biochemical and biophysical research communications 449 (2), 256-261; 2014
TJ Hossain*, MK Alam, D Sikdar
Continental J. Food Science and Technology 5 (2), 6-17; 2011
M Zobaer, F Ali, A Hossain, TJ Hossain
Biochimica et Biophysica Acta
Frontiers in Bioengineering and Biotechnology
Current Microbiology
Applied Food Biotechnology
Jordan Journal of Biological Sciences
Biodiversitas Journal of Biological Diversity
etc.