Lymphoma in hamsters

In pet hamsters (Syrian hamsters), lymphoma is the most common type of neoplasia. There are three variations of lymphoma. 

• Cutaneous lymphoma: Lethargy, anorexia, weight loss, and patchy alopecia are seen in affected animals.    

• Hematopoietic system: These tumors involve the thymus, thoracic lymph nodes, mesenteric lymph nodes, superficial lymph nodes, spleen, liver and other sites.   

• Polyomavirus (HaPV): Hamsters with this virus appear thin often with palpable masses in their abdomen.

Base a diagnosis of lymphoma on the history, clinical findings, and results of diagnostic testing. If enlarged lymph nodes are noted, perform a fine needle aspiration for cytologic examination. Cutaneous lymphoma is best diagnosed by a full-thickness skin biopsy.

For treatment, prednisolone (1–2 mg/kg PO every 12–24 hours) may result in a short period of remission. There are no detailed reports regarding other chemotherapy.

References:

Miwa, Y., & Mayer, J. (2020). Hamsters and gerbils. Ferrets, Rabbits and Rodents-E-Book: Clinical Medicine and Surgery, 368.