Research Vision:

We study the interaction between obesity, adipose tissue inflammation, insulin resistance, and cancer.

Research Areas:

• Adipose tissue inflammation

• Health services research

• NASH

Research Publications:

1. Ikramuddin S, Korner J, Lee W, et al. Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia: The Diabetes Surgery Study Randomized Clinical Trial. JAMA. 2013;309(21):2240–2249. doi:10.1001/jama.2013.5835

2. Jahansouz C, Staley C, Kizy S, Xu H, Hertzel AV, Coryell J, Singroy S, Hamilton M, DuRand M, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S. Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy. Ann Surg. 2019 Jun;269(6):1092-1100. doi: 10.1097/SLA.0000000000002729. PMID: 31082907.

3. Leslie D, Wise E, Sheka A, Abdelwahab H, Irey R, Benner A, Ikramuddin S. Gastroesophageal Reflux Disease Outcomes After Vertical Sleeve Gastrectomy and Gastric Bypass. Ann Surg. 2021 Oct 1;274(4):646-653. doi: 10.1097/SLA.0000000000005061. PMID: 34506320.

4. Ikramuddin S, Korner J, Lee W, et al. Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study. JAMA. 2018;319(3):266–278. doi:10.1001/jama.2017.20813

5. Sheka AC, Hameed B, Ikramuddin S. Nonalcoholic Steatohepatitis—Reply. JAMA. 2020;324(9):899–900. doi:10.1001/jama.2020.10437