Research Vision:

Dr. Melton-Meaux's research focuses on the development and application of informatics techniques and data analytics to transform and provide higher value clinical care. She serves as Director of the Center for Learning Health System Sciences, which focuses on creating value in health delivery systems by leveraging existing evidence, gathering new knowledge, and applying this work into direct population health action. She co-leads the Natural Language Processing / Information Extraction (NLP/IE) Program, a team of investigators, researchers, developers, and students who use NLP to process, extract, and encode information from unstructured biomedical and clinical texts. At M Health Fairview, she also leads the Optimal Care program which includes population health, clinical variation reduction including care maps and guidelines, and value-based care.

Research Areas:

• Learning health systems

• Clinical and research informatics

• Data analytics and value-based care

Research Publications:

1. Zhu Y, Simon GJ, Wick EC, Abe-Jones Y, Najafi N, Sheka A, Tourani R, Skube SJ, Hu Z, Melton GB. Applying Machine Learning Across Sites: External Validation of a Surgical Site Infection Detection Algorithm. J Am Coll Surg. 2021 Jun;232(6):963-971.e1. doi: 10.1016/j.jamcollsurg.2021.03.026. Epub 2021 Apr 5. PMID: 33831539.

2. Skube SJ, Hu Z, Simon GJ, Wick EC, Arsoniadis EG, Ko CY, Melton GB. Accelerating Surgical Site Infection Abstraction With a Semi-automated Machine-learning Approach. Ann Surg. 2020 Oct 14. doi: 10.1097/SLA.0000000000004354. Epub ahead of print. PMID: 33074897.

3. Annis T, Pleasants S, Hultman G, Lindemann E, Thompson JA, Billecke S, Badlani S, Melton GB. Rapid implementation of a COVID-19 remote patient monitoring program. J Am Med Inform Assoc. 2020 Aug 1;27(8):1326-1330. doi: 10.1093/jamia/ocaa097. PMID: 32392280; PMCID: PMC7239139.

4. Tignanelli CJ, Silverman GM, Lindemann EA, Trembley AL, Gipson JC, Beilman G, Lyng JW, Finzel R, McEwan R, Knoll BC, Pakhomov S, Melton GB. Natural Language Processing of Prehospital Emergency Medical Services Trauma Records Allows for Automated Characterization of Treatment Appropriateness J Trauma Acute Care Surg. 2020 May;88(5):607-614. PMID: 31977990.

5. Hultman GM, Marquard JL, Lindemann E, Arsoniadis E, Pakhomov S, Melton GB. Challenges and Opportunities to Improve the Clinician Experience Reviewing Electronic Progress Notes. Appl Clin Inform. 2019 May;10(3):446-453. doi: 10.1055/s-0039-1692164. Epub 2019 Jun 19. PMID: 31216591.